Katyal Monica, Leibowitz Ruth, Venters Homer
1 Division of Correctional Health Services, New York City Health + Hospitals, New York, NY, USA.
J Correct Health Care. 2018 Apr;24(2):156-170. doi: 10.1177/1078345818763868. Epub 2018 Apr 10.
In the United States, latent tuberculosis infection (LTBI) detection in correctional settings is a public health priority. Interferon gamma release assay (IGRA)-based LTBI screening was introduced in New York City jails in 2011 to 2012, replacing historically used tuberculin skin testing (TST), which was associated with substantial incomplete screening rates. This retrospective, cross-sectional study evaluated LTBI screening outcomes and correlates of positivity in 40,986 persons newly incarcerated in 2011 to 2013. Of 35,090 eligible patients tested (96.4%), final results were 6.3% positive, 93.4% negative, and 0.2% indeterminate. In multivariable regression modeling, sex, age, race/ethnicity, nativity, marital status, prior jail incarceration, and HIV status were correlated with positivity. IGRA-based screening yielded high screening and low indeterminate test rates and may be recommended in correctional and other settings where TST is currently used.
在美国，惩教机构中的潜伏性结核感染（LTBI）检测是一项公共卫生重点工作。基于干扰素γ释放试验（IGRA）的LTBI筛查于2011年至2012年在纽约市监狱引入，取代了历史上使用的结核菌素皮肤试验（TST），后者存在相当高的筛查不完整率。这项回顾性横断面研究评估了2011年至2013年新入狱的40986人的LTBI筛查结果及阳性相关因素。在35090名符合条件接受检测的患者中（96.4%），最终结果为6.3%阳性、93.4%阴性和0.2%不确定。在多变量回归模型中，性别、年龄、种族/族裔、出生地、婚姻状况、既往入狱史和HIV状态与阳性相关。基于IGRA的筛查具有高筛查率和低不确定检测率，可能推荐在目前使用TST的惩教及其他场所使用。
