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乳糜泻中的内分泌病:当内分泌科医生看到胃肠病医生看不见的东西时。

Endocrinopathies in celiac disease: When the endocrinologist sees what is invisible to the gastroenterologist.

作者信息

Khater Dooa

机构信息

.

出版信息

Acta Biomed. 2018 Mar 27;89(1):117-121. doi: 10.23750/abm.v89i1.7119.

Abstract

Celiac disease (CD) is a systemic, immune mediated and genetically determined small intestinal disorder characterized by intolerance to dietary gluten that generally presents with gastrointestinal symptoms in young children and extra-intestinal manifestations. Furthermore, there is close association between CD and endocrine diseases, including diabetes, autoimmune thyroid diseases, growth and pubertal disorders, etc. probably due to the presence of a common genetic predisposition. The present review aims to highlight and give more insight to the endocrine changes in CD, especially when there are few or no gastrointestinal symptoms and to emphasize on screening opportunities in some endocrine diseases.

摘要

乳糜泻(CD)是一种全身性、免疫介导且由基因决定的小肠疾病,其特征为对膳食麸质不耐受,通常在幼儿期出现胃肠道症状及肠外表现。此外,CD与内分泌疾病密切相关,包括糖尿病、自身免疫性甲状腺疾病、生长及青春期障碍等,这可能是由于存在共同的遗传易感性。本综述旨在突出并更深入了解CD中的内分泌变化,尤其是在胃肠道症状很少或没有的情况下,并强调某些内分泌疾病的筛查机会。

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本文引用的文献

1
Gut-thyroid axis and celiac disease.肠-甲状腺轴与乳糜泻
Endocr Connect. 2017 May;6(4):R52-R58. doi: 10.1530/EC-17-0021. Epub 2017 Apr 5.
4
Celiac Disease in Women With Infertility: A Meta-Analysis.不孕女性中的乳糜泻:一项荟萃分析。
J Clin Gastroenterol. 2016 Jan;50(1):33-9. doi: 10.1097/MCG.0000000000000285.
9
Recent advances in celiac disease.最近关于乳糜泻的进展。
World J Gastroenterol. 2011 May 14;17(18):2259-72. doi: 10.3748/wjg.v17.i18.2259.

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