抗有丝分裂黏附提供了分裂细胞的分子记忆。
Mitosis-Resistant Adhesions Provide Molecular Memory to Dividing Cells.
机构信息
Turku Centre for Biotechnology, University of Turku and Åbo Akademi University, Turku, Finland.
Turku Centre for Biotechnology, University of Turku and Åbo Akademi University, Turku, Finland; Department of Biochemistry, University of Turku, Turku, Finland.
出版信息
Dev Cell. 2018 Apr 9;45(1):5-7. doi: 10.1016/j.devcel.2018.03.015.
During mitosis, animal cells disassemble focal adhesions and round up while remaining attached to the substrata via actin cables and unknown adhesive structures. In this issue of Developmental Cell, Dix et al. (2018) describe integrin-positive adhesions, devoid of classical focal adhesion components, that persist throughout mitosis to contribute to re-spreading.
在有丝分裂过程中，动物细胞通过肌动蛋白电缆和未知的黏附结构与基质相连，同时解聚黏着斑并发生细胞形态变化。在本期的《发育细胞》中，Dix 等人（2018）描述了整联蛋白阳性黏附物，它们缺乏经典黏着斑成分，但在整个有丝分裂过程中持续存在，有助于重新铺展。
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