Department of Kayachikitsa, Faculty of Ayurveda, Banaras Hindu University, Varanasi, 221005, India.
Cell Physiology Laboratory, Department of Zoology, Institute of Science, Banaras Hindu University, Varanasi, 221005, U.P., India.
Biomed Pharmacother. 2018 Jul;103:46-49. doi: 10.1016/j.biopha.2018.04.003. Epub 2018 Apr 7.
Stress is deeply rooted in the society and women are frequently exposed to psychological, physical and physiological stressors. Psychological stress disturbs reproductive health by inducing generation of reactive oxygen species (ROS) and thereby oxidative stress (OS). The increased OS may affect physiology of ovary, oocyte quality and cause female reproductive health disorders. To overcome stress-mediated reproductive health disorders in women, shatavari (Asparagus racemosus) is frequently recommended in Ayurvedic system of medicine. Although shatavari is one of the major health tonics and most popular rasayana drugs to treat reproductive ailments of women, underlying mechanism of shatavari action at the level of ovary remains poorly understood. Based on the existing studies, we propose that shatavari may improve female reproductive health complications including hormonal imbalance, polycystic ovarian syndrome (PCOS), follicular growth and development, oocyte quality and infertility possibly by reducing OS level and increasing antioxidants level in the body. Further studies are required to elucidate the mechanism of shatavari actions at the level of ovary and oocyte that directly impacts the reproductive health of women.
压力深深扎根于社会中，女性经常面临心理、生理和生理压力源。心理压力通过诱导活性氧（ROS）的产生而扰乱生殖健康，从而导致氧化应激（OS）。增加的 OS 可能会影响卵巢的生理学、卵子质量并导致女性生殖健康障碍。为了克服女性介导的生殖健康障碍，在阿育吠陀医学系统中经常推荐使用 Shatavari（天门冬属植物）。尽管 Shatavari 是主要的保健品之一，也是治疗女性生殖疾病最受欢迎的延年益寿药物之一，但 Shatavari 在卵巢水平的作用机制仍知之甚少。基于现有研究，我们提出 Shatavari 可能通过降低体内 OS 水平和增加抗氧化剂水平来改善包括激素失衡、多囊卵巢综合征（PCOS）、卵泡生长和发育、卵子质量和不孕在内的女性生殖健康并发症。需要进一步的研究来阐明 Shatavari 在卵巢和卵子水平的作用机制，这直接影响女性的生殖健康。
