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用于评估军事和创伤伤口清创情况的自体荧光成像

Autofluorescence Imaging for Evaluating Debridement in Military and Trauma Wounds.

作者信息

Blumenthal Emily, Jeffery Steven

机构信息

University College London, Division of Surgery & Interventional Science, Gower Street, Bloomsbury, London, WC1E 6BT, UK.

Birmingham Burn Centre, The Queen Elizabeth Hospital, Mindelsohn Way, Birmingham, B15 2TH, UK.

出版信息

Mil Med. 2018 Mar 1;183(suppl_1):429-432. doi: 10.1093/milmed/usx145.

DOI:10.1093/milmed/usx145
PMID:29635558
Abstract

BACKGROUND

Mechanisms for military injury have evolved in the past century. Debridement is the gold standard for preparing a clean wound bed, decreasing the bacterial load, and reducing the likelihood of infection. However, bacteria may continue to linger in these wounds. The MolecuLight i:X Imaging Device uses the principle of autofluorescence to detect bacteria under violet light. Thus, visualizing bacteria will not only guide clinicians in their management of the wound but it will also serve as a means of evaluating debridement efforts. We hope to improve traumatic wound management by targeting debridement and assessing its quality.

METHODS

We describe the use of the MolecuLight i:X to photograph wounds under standard and violet light in three patients. Images were captured before and after debridement. Microbiology swabs were collected to correlate the bacteria found in the images to the wounds.

RESULTS

The post-debridement images demonstrate a marked decrease or complete removal of bacteria. The microbiology swabs confirmed the pre-debridement presence of bacteria.

CONCLUSIONS

The MolecuLight i:X shows promise for debridement evaluation. The use of the MolecuLight i:X may reduce the likelihood of infection, thus having positive implications for military and trauma wounds.

摘要

背景

在过去的一个世纪里,军事损伤机制不断演变。清创术是准备清洁伤口床、减少细菌负荷以及降低感染可能性的金标准。然而,细菌可能会继续在这些伤口中留存。MolecuLight i:X成像设备利用自发荧光原理在紫光下检测细菌。因此,可视化细菌不仅能指导临床医生处理伤口,还将作为评估清创效果的一种手段。我们希望通过针对清创术并评估其质量来改善创伤性伤口的处理。

方法

我们描述了在三名患者中使用MolecuLight i:X在标准光和紫光下拍摄伤口的情况。在清创前后拍摄图像。采集微生物拭子以将图像中发现的细菌与伤口相关联。

结果

清创后的图像显示细菌明显减少或完全清除。微生物拭子证实了清创前伤口中存在细菌。

结论

MolecuLight i:X在清创评估方面显示出前景。使用MolecuLight i:X可能会降低感染的可能性,因此对军事和创伤伤口具有积极意义。

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