Nuffield Department of Obstetrics and Gynaecology, University of Oxford, John Radcliffe Hospital, Headington, Oxford, UK.
Int J Nanomedicine. 2018 Mar 29;13:1963-1983. doi: 10.2147/IJN.S97572. eCollection 2018.
State-of-the-art applications of nanomedicine have the potential to revolutionize the diagnosis, prevention, and treatment of a range of conditions and diseases affecting women's health. In this review, we provide a synopsis of potential applications of nanomedicine in some of the most dominant fields of women's health: mental health, sexual health, reproductive medicine, oncology, menopause-related conditions and dementia. We explore published studies arising from in vitro and in vivo experiments, and clinical trials where available, to reveal novel and highly promising therapeutic applications of nanomedicine in these fields. For the first time, we summarize the growing body of evidence relating to the use of nanomaterials as experimental tools for the detection, prevention, and treatment of significant diseases and conditions across the life course of a cisgender woman, from puberty to menopause; revealing the far-reaching and desirable theoretical impact of nanomedicine across different medical disciplines. We also present an overview of potential concerns regarding the therapeutic applications of nanomedicine and the factors currently restricting the growth of applied nanomedicine.
纳米医学的最新应用有潜力彻底改变一系列影响女性健康的疾病和病症的诊断、预防和治疗。在这篇综述中,我们概述了纳米医学在女性健康的一些主要领域中的潜在应用:心理健康、性健康、生殖医学、肿瘤学、绝经相关疾病和痴呆症。我们探讨了已发表的研究,包括来自体外和体内实验的研究,以及有临床试验的研究,以揭示纳米医学在这些领域中具有创新性和非常有前途的治疗应用。这是第一次总结与使用纳米材料作为实验工具有关的越来越多的证据,这些证据涉及跨性别女性整个生命周期(从青春期到绝经期)的重大疾病和病症的检测、预防和治疗;揭示了纳米医学在不同医学学科中的深远和理想的理论影响。我们还概述了纳米医学治疗应用的潜在问题以及当前限制应用纳米医学发展的因素。