先进的磁共振成像（MRI）技术：技术原理及其在纳米医学中的应用
Advanced Magnetic Resonance Imaging (MRI) Techniques: Technical Principles and Applications in Nanomedicine.
作者信息
Bruno Federico, Granata Vincenza, Cobianchi Bellisari Flavia, Sgalambro Ferruccio, Tommasino Emanuele, Palumbo Pierpaolo, Arrigoni Francesco, Cozzi Diletta, Grassi Francesca, Brunese Maria Chiara, Pradella Silvia, di S Stefano Maria Luisa Mangoni, Cutolo Carmen, Di Cesare Ernesto, Splendiani Alessandra, Giovagnoni Andrea, Miele Vittorio, Grassi Roberto, Masciocchi Carlo, Barile Antonio
机构信息
Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, 67100 L'Aquila, Italy.
Italian Society of Medical and Interventional Radiology (SIRM), SIRM Foundation, 20122 Milan, Italy.
出版信息
Cancers (Basel). 2022 Mar 23;14(7):1626. doi: 10.3390/cancers14071626.
In the last decades, nanotechnology has been used in a wide range of biomedical applications, both diagnostic and therapeutic. In this scenario, imaging techniques represent a fundamental tool to obtain information about the properties of nanoconstructs and their interactions with the biological environment in preclinical and clinical settings. This paper reviews the state of the art of the application of magnetic resonance imaging in the field of nanomedicine, as well as the use of nanoparticles as diagnostic and therapeutic tools, especially in cancer, including the characteristics that hinder the use of nanoparticles in clinical practice.
在过去几十年中，纳米技术已广泛应用于各种生物医学领域，包括诊断和治疗。在这种情况下，成像技术是在临床前和临床环境中获取有关纳米结构特性及其与生物环境相互作用信息的基本工具。本文综述了磁共振成像在纳米医学领域的应用现状，以及纳米颗粒作为诊断和治疗工具的应用，特别是在癌症方面的应用，包括阻碍纳米颗粒在临床实践中应用的特性。
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