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非依赖型和依赖型每日大麻使用者在心理健康方面存在差异,但前瞻性记忆能力无差异。

Non-Dependent and Dependent Daily Cannabis Users Differ in Mental Health but Not Prospective Memory Ability.

作者信息

Braidwood Ruth, Mansell Samantha, Waldron Jon, Rendell Peter G, Kamboj Sunjeev K, Curran H Valerie

机构信息

Clinical Psychopharmacology Unit (CPU), University College London, London, United Kingdom.

Cognition and Emotion Research Centre, Australian Catholic University, Melbourne, VIC, Australia.

出版信息

Front Psychiatry. 2018 Mar 27;9:97. doi: 10.3389/fpsyt.2018.00097. eCollection 2018.

Abstract

Research suggests that daily cannabis users have impaired memory for past events, but it is not clear whether they are also impaired in prospective memory (PM) for future events. The present study examined PM in daily cannabis users who were either dependent ( = 18) or non-dependent ( = 18), and compared them with non-using controls ( = 18). The effect of future event simulation (FES) on PM performance was also examined. Participants were matched across groups on age, gender, and highest level of education. The virtual week (VW) was used to objectively assess PM abilities, both at baseline and following FES. Other measures used were: cannabis use variables, immediate and delayed prose recall, phonemic and category fluency, spot-the-word test (premorbid intelligence), Beck Depression Inventory, Beck Anxiety Inventory, and a measure of schizotypy (Oxford-Liverpool Inventory of Feelings and Experiences: unusual experiences subscale). No group differences were found in PM performance on the VW, and FES did not improve PM performance in any group. Dependent cannabis users scored higher on depression, anxiety, and schizotypy than both other groups with non-dependent cannabis users scoring at a similar level to controls. There were no group differences in alcohol use. Findings suggest that when carefully matched on baseline variables, and not differing in premorbid IQ or alcohol use, young, near-daily cannabis users do not differ from non-using controls in PM performance.

摘要

研究表明,日常吸食大麻者对过去事件的记忆受损,但尚不清楚他们对未来事件的前瞻性记忆(PM)是否也受到损害。本研究对18名依赖大麻的日常使用者和18名不依赖大麻的日常使用者的前瞻性记忆进行了检测,并将他们与18名不吸食大麻的对照组进行比较。还研究了未来事件模拟(FES)对前瞻性记忆表现的影响。研究根据年龄、性别和最高学历对各组参与者进行匹配。使用虚拟周(VW)在基线和未来事件模拟后客观评估前瞻性记忆能力。使用的其他测量方法包括:大麻使用变量、即时和延迟散文回忆、音素流畅性和类别流畅性、找词测试(病前智力)、贝克抑郁量表、贝克焦虑量表以及一种精神分裂症倾向测量方法(牛津-利物浦情感与体验量表:异常体验子量表)。在虚拟周的前瞻性记忆表现上未发现组间差异,未来事件模拟也未改善任何一组的前瞻性记忆表现。依赖大麻的使用者在抑郁、焦虑和精神分裂症倾向上的得分高于其他两组,不依赖大麻的使用者得分与对照组相似。在酒精使用方面未发现组间差异。研究结果表明,在根据基线变量仔细匹配且病前智商或酒精使用无差异的情况下,年轻的近日常吸食大麻者在前瞻性记忆表现上与不吸食大麻的对照组没有差异。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3bd9/5880932/a02e7aaf8518/fpsyt-09-00097-g001.jpg

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