用于消融室性心动过速的非侵入性心脏放射治疗：电生理学中的一种新治疗模式。
Non-invasive Cardiac Radiation for Ablation of Ventricular Tachycardia: a New Therapeutic Paradigm in Electrophysiology.
作者信息
Kim Eun-Jeong, Davogustto Giovanni, Stevenson William G, John Roy M
机构信息
Both authors contributed equally to this work.
Division of Cardiovascular Medicine, Department of Medicine, Vanderbilt University Medical CenterNashville, TN, USA.
出版信息
Arrhythm Electrophysiol Rev. 2018 Mar;7(1):8-10. doi: 10.15420/aer.7.1.EO1.
Abstract
Non-invasive ablation of cardiac tissue to control ventricular tachycardia (VT) is a novel therapeutic consideration in the management of ventricular arrhythmias associated with structural heart disease. The technique involves the use of stereotactic radiotherapy delivered to VT substrates. Although invasive mapping can be used to identify the target, the use of non-invasive ECG and imaging techniques combined with multi-electrode body-surface ECG recordings offers the potential of a completely non-invasive approach. Early case series have demonstrated a consistent decrease in VT burden and sufficient early safety to allow more detailed multicenter studies. Such studies are currently in progress to further evaluate this promising technology.
摘要
非侵入性心脏组织消融以控制室性心动过速（VT）是治疗与结构性心脏病相关的室性心律失常的一种新的治疗思路。该技术涉及使用立体定向放射疗法作用于室性心动过速病灶。虽然侵入性标测可用于识别靶点，但将非侵入性心电图和成像技术与多电极体表心电图记录相结合，提供了一种完全非侵入性方法的可能性。早期病例系列研究已表明室性心动过速发作次数持续减少，且早期安全性足以开展更详细的多中心研究。此类研究目前正在进行中，以进一步评估这项前景广阔的技术。
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