Choi Eun-Young Karen, McKenna Barbara J
From the Department of Pathology, University of Michigan, Ann Arbor.
Arch Pathol Lab Med. 2015 Oct;139(10):1242-7. doi: 10.5858/arpa.2015-0204-RA.
Olmesartan is an antihypertensive medication belonging to the angiotensin II receptor blocker class of drugs that has recently been associated with severe enteropathy. Olmesartan-associated enteropathy is uncommon and may be difficult to recognize because of its clinical and histologic similarities to other clinical entities, including celiac sprue and autoimmune enteropathy. The purpose of this article is to review the clinical and histologic findings of olmesartan-associated enteropathy that have been reported in the literature and to discuss clinical entities to consider in the differential diagnosis of olmesartan-associated enteropathy.
奥美沙坦是一种降压药物，属于血管紧张素II受体阻滞剂类药物，最近被发现与严重肠病有关。奥美沙坦相关肠病并不常见，由于其临床和组织学表现与其他临床疾病（包括乳糜泻和自身免疫性肠病）相似，可能难以识别。本文的目的是回顾文献中报道的奥美沙坦相关肠病的临床和组织学表现，并讨论在奥美沙坦相关肠病鉴别诊断中需要考虑的临床疾病。
