Hu Jiayu, Chen Zhenxian, Xin Hua, Zhang Qida, Jin Zhongmin
1 State Key Laboratory for Manufacturing System Engineering, School of Mechanical Engineering, Xi'an Jiaotong University, Xi'an, China.
2 Key Laboratory of Road Construction Technology and Equipment (Ministry of Education), School of Mechanical Engineering, Chang'an University, Xi'an, China.
Proc Inst Mech Eng H. 2018 May;232(5):508-519. doi: 10.1177/0954411918767695. Epub 2018 Apr 11.
Detailed knowledge of the in vivo loading and kinematics in the knee joint is essential to understand its normal functions and the aetiology of osteoarthritis. Computer models provide a viable non-invasive solution for estimating joint loading and kinematics during different physiological activities. However, the joint loading and kinematics of the tibiofemoral and patellofemoral joints during a gait cycle were not typically investigated concurrently in previous computational simulations. In this study, a natural knee architecture was incorporated into a lower extremity musculoskeletal multibody dynamics model based on a force-dependent kinematics approach to investigate the contact mechanics and kinematics of a natural knee joint during a walking cycle. Specifically, the contact forces between the femoral/tibial articular cartilages and menisci and between the femoral and tibial/patellar articular cartilages were quantified. The contact forces and kinematics of the tibiofemoral and patellofemoral joints and the muscle activations and ligament forces were predicted simultaneously with a reasonable level of accuracy. The developed musculoskeletal multibody dynamics model with a natural knee architecture can serve as a potential platform for assisting clinical decision-making and postoperative rehabilitation planning.
深入了解膝关节的体内负荷和运动学对于理解其正常功能以及骨关节炎的病因至关重要。计算机模型为估算不同生理活动期间的关节负荷和运动学提供了一种可行的非侵入性解决方案。然而，在先前的计算模拟中，通常不会同时研究步态周期中胫股关节和髌股关节的关节负荷和运动学。在本研究中，基于力相关运动学方法，将自然膝关节结构纳入下肢肌肉骨骼多体动力学模型，以研究步行周期中自然膝关节的接触力学和运动学。具体而言，量化了股骨/胫骨关节软骨与半月板之间以及股骨与胫骨/髌骨关节软骨之间的接触力。同时以合理的准确度预测了胫股关节和髌股关节的接触力和运动学以及肌肉激活和韧带力。所开发的具有自然膝关节结构的肌肉骨骼多体动力学模型可作为辅助临床决策和术后康复计划的潜在平台。
