Campitiello Ferdinando, Mancone Manfredi, Corte Angela Della, Guerniero Raffaella, Canonico Silvestro
Department of Medical, Surgical, Neurologic, Metabolic and Aging Sciences, University of Campania, 'Luigi Vanvitelli', Piazza Miraglia 2, Napoli, Campania, Italy.
Professor, Department of Medical, Surgical, Neurologic, Metabolic and Aging Sciences, University of Campania, 'Luigi Vanvitelli', Piazza Miraglia 2, Napoli, Campania, Italy.
J Wound Care. 2018 Apr 2;27(4):222-228. doi: 10.12968/jowc.2018.27.4.222.
This study evaluated the use of ultrasonic debridement in patients with diabetic foot ulcers (DFU).
In this prospective, single-arm, open-label study, all patients with DFUs underwent wound debridement by ultrasonic debridement system (SonicOne OR Ultrasonic debridement system). Wherever possible, the edges were approximated by means of stitches. In other cases, the surgical breach healed by secondary intention, or a partial thickness skin graft (with or without Integra Dermal Regeneration Template or Integra Flowable Wound Matrix) was applied, and subsequently healed by primary intention.
We assessed 15 patients with a DFU. The time required for debridement was short (an average 15.06±4.02 minutes). Complete wound healing (defined as 100% re-epithelialisation) was achieved in all 15 cases. Median time to heal was 39.20±16.05 days. The ultrasonic debridement system was found to show adequate debridement while preserving more viable tissue to promote rapid healing.
Our findings show that the device demonstrates advantages in the reduction of debridement times, and efficacy in safely preserving the viable tissue, with a low complication rate in surgery of DFUs. A study that uses a larger cohort is required to fully evaluate the effectiveness, or otherwise, of the ultrasonic debridement system.
本研究评估了超声清创术在糖尿病足溃疡（DFU）患者中的应用。
在这项前瞻性、单臂、开放标签研究中，所有DFU患者均通过超声清创系统（SonicOne或超声清创系统）进行伤口清创。只要有可能，边缘就通过缝合进行拉拢。在其他情况下，手术创口通过二期愈合，或应用部分厚度皮肤移植（有或没有Integra真皮再生模板或Integra可流动伤口基质），随后一期愈合。
我们评估了15例DFU患者。清创所需时间较短（平均15.06±4.02分钟）。所有15例患者均实现了完全伤口愈合（定义为100%再上皮化）。中位愈合时间为39.20±16.05天。发现超声清创系统在进行充分清创的同时能保留更多有活力的组织以促进快速愈合。
我们的研究结果表明，该设备在减少清创时间方面具有优势，在安全保留有活力组织方面有效，在DFU手术中并发症发生率较低。需要进行一项使用更大队列的研究来全面评估超声清创系统的有效性与否。
