Hsiung C H, Karow W G, Gentry W C, Tsui M, Smith D W, Tejada R I
Southern California Fertility Institute, Los Angeles 90025.
J In Vitro Fert Embryo Transf. 1987 Dec;4(6):312-5. doi: 10.1007/BF01555376.
The first case of a genetic abnormality in a 3-year in vitro fertilization and embryo transfer program was diagnosed after routine amniocentesis of a 38-year-old patient. The G-banded karyotype analysis gave 47, XY, +21, which constitutes an abnormal chromosome pattern consistent with Down syndrome.
在一项为期3年的体外受精和胚胎移植项目中，首例基因异常病例是在对一名38岁患者进行常规羊膜穿刺术后确诊的。G带核型分析结果显示为47, XY, +21，这是一种与唐氏综合征相符的异常染色体模式。
