南加州生育研究所体外受精和胚胎移植项目中首例唐氏综合征报告病例。

The first reported case of Down syndrome in the Southern California Fertility Institute's in vitro fertilization and embryo transfer program.

作者信息

Hsiung C H, Karow W G, Gentry W C, Tsui M, Smith D W, Tejada R I

机构信息

Southern California Fertility Institute, Los Angeles 90025.

出版信息

J In Vitro Fert Embryo Transf. 1987 Dec;4(6):312-5. doi: 10.1007/BF01555376.

DOI:10.1007/BF01555376

PMID:2963880

Abstract

The first case of a genetic abnormality in a 3-year in vitro fertilization and embryo transfer program was diagnosed after routine amniocentesis of a 38-year-old patient. The G-banded karyotype analysis gave 47, XY, +21, which constitutes an abnormal chromosome pattern consistent with Down syndrome.

摘要

在一项为期3年的体外受精和胚胎移植项目中，首例基因异常病例是在对一名38岁患者进行常规羊膜穿刺术后确诊的。G带核型分析结果显示为47, XY, +21，这是一种与唐氏综合征相符的异常染色体模式。