Guido William
Department of Anatomical Sciences and Neurobiology, University of Louisville School of Medicine , Louisville, Kentucky.
J Neurophysiol. 2018 Jul 1;120(1):211-225. doi: 10.1152/jn.00651.2017. Epub 2018 Apr 11.
The dorsal lateral geniculate nucleus (dLGN) of the thalamus is the exclusive relay of retinal information en route to the visual cortex. Although much of our understanding about dLGN comes from studies done in higher mammals, such as the cat and primate, the mouse as a model organism has moved to the forefront as a tractable experimental platform to examine cell type-specific relations. This review highlights our current knowledge about the development, structure, and function of the mouse dLGN.
丘脑的背外侧膝状核(dLGN)是视网膜信息通向视觉皮层的唯一中继站。尽管我们对dLGN的许多了解来自于对高等哺乳动物(如猫和灵长类动物)的研究,但小鼠作为一种模式生物,已成为研究细胞类型特异性关系的易于操作的实验平台而处于前沿地位。这篇综述重点介绍了我们目前对小鼠dLGN的发育、结构和功能的认识。