Wauters Robert H, Banks Taylor A, Lomasney Evelyn M
Internal Medicine, Walter Reed National Military Medical Center, Bethesda, Maryland, USA.
Allergy/ Immunology, Walter Reed National Military Medical Center, Bethesda, Maryland, USA.
BMJ Case Rep. 2018 Apr 11;2018:bcr-2017-222370. doi: 10.1136/bcr-2017-222370.
Food-dependent exercise-induced anaphylaxis (FDEIAn), first reported in 1979, is a condition defined by the consumption of a trigger food with temporally related exercise that results in an immediate hypersensitivity (type 1) reaction in the setting of the trigger food being tolerated independent of exercise and exercise being tolerated in the absence of trigger food consumption. The most common trigger food in the west is wheat and shellfish in Asia. The exact mechanism of FDEIAn is unknown, though several hypotheses exist. Cofactors such as non-steroidal anti-inflammatory drug use, alcohol consumption and others have been associated with reported cases.
食物依赖运动诱发的过敏反应(FDEIAn)于1979年首次报道,是一种因食用引发食物并在时间上与运动相关联而引发的病症,在该病症中,引发食物在不依赖运动的情况下可被耐受,且运动在未食用引发食物时也可被耐受,但食用引发食物并运动后会导致速发型超敏反应(1型)。在西方,最常见的引发食物是小麦,在亚洲则是贝类。尽管存在多种假说,但FDEIAn的确切机制尚不清楚。非甾体抗炎药使用、饮酒等辅助因素与已报道的病例有关。