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一例继发性甲状旁腺功能亢进症中酷似家族性颌骨多囊病的下颌骨异常巨大棕色瘤

Unusually Large Brown tumor of Mandible in a Case of Secondary Hyperparathyroidism Mimicking Cherubism.

作者信息

Singhal Alka Ashmita, Baijal Sanjay Saran, Sarin Deepak, Pathak Atul

机构信息

Medanta Division of Radiology and Nuclear Medicine, Medanta The Medicity Hospital, Gurugram, Delhi, NCR, India.

出版信息

Indian J Nucl Med. 2018 Apr-Jun;33(2):132-135. doi: 10.4103/ijnm.IJNM_145_17.

Abstract

We report here a case of unusually large brown tumor of mandible mimicking cherubism in a patient with secondary hyperparathyroidism (HPT). The patient is a young male with a large head and a protruding jaw with an open mouth appearance. Initial clinical appearance looked like cherubism. However further clinical, biochemical, and radiological evaluation revealed a large brown tumor in a case of prolonged secondary HPT, which was confirmed on histopathology. All of the typical advanced radiological features of HPT were noted, highlighting the severity of progression of the disease. This case emphasizes the need for surveillance of serum calcium levels on routine biochemical investigations as to enable an early diagnosis of HPT. With timely proper management, such cases should be on the decline in the future.

摘要

我们在此报告一例继发性甲状旁腺功能亢进(HPT)患者中出现的异常巨大的下颌骨棕色瘤,其表现类似下颌骨肥大症。该患者为年轻男性,头部较大,下颌前突,呈张口状。初始临床表现看似下颌骨肥大症。然而,进一步的临床、生化及放射学评估显示,这是一例长期继发性HPT患者出现的巨大棕色瘤,组织病理学检查得以证实。HPT所有典型的晚期放射学特征均被发现,凸显了疾病进展的严重性。该病例强调了在常规生化检查中监测血清钙水平以早期诊断HPT的必要性。通过及时恰当的管理,此类病例未来应会减少。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0ad1/5883431/01a63d3a90bd/IJNM-33-132-g001.jpg

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