非出血性卒中和心房颤动患者左心室舒张功能障碍的评估
The evaluation of left ventricular diastolic dysfunction in patients with non-hemorrhagic stroke and atrial fibrillation.
作者信息
Najafi-Dalui Mahdi, Shemirani Hasan, Zavar Reyhaneh, Eghbal Ali
机构信息
Resident, Cardiac Rehabilitation Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran.
Assistant Professor, Hypertension Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran.
出版信息
ARYA Atheroscler. 2017 Nov;13(6):299-303.
BACKGROUND
Atrial fibrillation (AF) is the most common tachyarrhythmia and an important risk factor for thromboembolic stroke. CHA2DS2-VASc score was introduced for assessment of embolic events and as criteria for starting anticoagulants. This study was performed to evaluate the left ventricular diastolic dysfunction (LVDD) in patients with non-hemorrhagic stroke and AF.
METHODS
This cross-sectional study consisted of 76 consecutive patients with suspected non-hemorrhagic stroke referred to the Cardiology Department of Alzahra and Ayatollah Kashani hospitals in Isfahan, Iran, during 2015-2016. Demographic, anthropometric and clinical characteristics were evaluated for all patients at baseline. CHA2DS2-VASc score was calculated for all. All eligible patients underwent transthoracic echocardiogram (TTE) and LVDD was measured in the patients.
RESULTS
The mean age of the patients was 64.64 ± 5.95 years and 28 subjects (36.8%) were women. The most common underlying disease in the patients was hypertension (HTN) (65.8%). Median (range) CHA2DS2-VASc score was 4 (1-7). Four patients (5.3%) had paroxysmal AF and 16 cases (21.1%) had LVDD. Analysis showed that LVDD in patients with non-hemorrhagic stroke and coexisting AF was not associated with CHA2DS2-VASc score (r = 0.151, P = 0.192).
CONCLUSION
LVDD is not associated with CHA2DS2-VASc score in patients with non-hemorrhagic stroke and coexisting AF.
背景
心房颤动（AF）是最常见的快速性心律失常，也是血栓栓塞性中风的重要危险因素。CHA2DS2-VASc评分被用于评估栓塞事件，并作为启动抗凝治疗的标准。本研究旨在评估非出血性中风合并房颤患者的左心室舒张功能障碍（LVDD）。
方法
这项横断面研究纳入了2015年至2016年期间转诊至伊朗伊斯法罕阿尔扎赫拉医院和阿亚图拉·卡尚尼医院心内科的76例疑似非出血性中风患者。在基线时对所有患者的人口统计学、人体测量学和临床特征进行评估。计算所有患者的CHA2DS2-VASc评分。所有符合条件的患者均接受经胸超声心动图（TTE）检查，并测量患者的LVDD。
结果
患者的平均年龄为64.64±5.95岁，28名受试者（36.8%）为女性。患者中最常见的基础疾病是高血压（HTN）（65.8%）。CHA2DS2-VASc评分中位数（范围）为4（1-7）。4例患者（5.3%）患有阵发性房颤，16例患者（21.1%）患有LVDD。分析表明，非出血性中风合并房颤患者的LVDD与CHA2DS2-VASc评分无关（r = 0.151，P = 0.192）。
结论
非出血性中风合并房颤患者的LVDD与CHA2DS2-VASc评分无关。
Zotero 插件