Key Laboratory of Agro-products Processing, Ministry of Agriculture, Laboratory of Food Chemistry and Nutrition Science, Institute of Food Science and Technology, Chinese Academy of Agricultural Sciences, 2 Yuan Ming Yuan West Road, Haidian District, Beijing 100193, China.
Department of Crop Genomics and Genetic Improvement, Biotechnology Research Institute, Chinese Academy of Agricultural Sciences, 12 Zhongguancun South Street, Haidian District, Beijing 100081, China.
Oxid Med Cell Longev. 2018 Feb 15;2018:9017828. doi: 10.1155/2018/9017828. eCollection 2018.
The antioxidant activity and inhibition of intracellular reactive oxygen species (ROS) of the total and individual phenolic compounds from Yuzi No. 7 sweet potato leaves were investigated in this study. Sweet potato leaf polyphenols possessed significantly higher antioxidant activity than ascorbic acid, tea polyphenols, and grape seed polyphenols. Among the individual phenolic compounds, caffeic acid showed the highest antioxidant activity, followed by monocaffeoylquinic acids and dicaffeoylquinic acids, while 3,4,5-tri-O-caffeoylquinic acid showed the lowest value. Sweet potato leaf polyphenols could significantly decrease the level of intracellular ROS in a dose-dependent manner. The order of the inhibiting effect of individual phenolic compounds on the intracellular ROS level was not in accordance with that of antioxidant activity, suggesting that there was no direct relationship between antioxidant activity and intracellular ROS-inhibiting effect. Sweet potato leaves could be a good source of biologically active polyphenols with multiple applications in the development of foods, health products, pharmaceuticals, and cosmetics.
本研究旨在探讨紫薯 7 号叶总酚和单体酚类化合物的抗氧化活性及对细胞内活性氧（ROS）的抑制作用。甘薯叶多酚的抗氧化活性明显高于抗坏血酸、茶多酚和葡萄籽多酚。在单体酚类化合物中，咖啡酸表现出最高的抗氧化活性，其次是单咖啡酰奎宁酸和二咖啡酰奎宁酸，而 3,4,5-三咖啡酰奎宁酸的活性最低。甘薯叶多酚能显著降低细胞内 ROS 水平，呈剂量依赖性。单体酚类化合物对细胞内 ROS 水平的抑制作用顺序与抗氧化活性不一致，表明抗氧化活性与细胞内 ROS 抑制作用之间没有直接关系。甘薯叶可能是一种具有多种应用的生物活性多酚的良好来源，可用于开发食品、保健品、药品和化妆品。
