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Patients' Experiences With HIV-positive to HIV-positive Organ Transplantation.患者接受从HIV阳性供体到HIV阳性受体的器官移植的经历。
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A prospective multicenter pilot study of HIV-positive deceased donor to HIV-positive recipient kidney transplantation: HOPE in action.一项针对 HIV 阳性已故供体向 HIV 阳性受者进行肾脏移植的前瞻性多中心试点研究：行动中的希望。
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Solid Organ Transplantation in HIV-Infected Recipients: History, Progress, and Frontiers.HIV 感染者的实体器官移植：历史、进展与前沿。
Curr HIV/AIDS Rep. 2019 Jun;16(3):191-203. doi: 10.1007/s11904-019-00440-x.

本文引用的文献

1
First Canadian Case Report of Kidney Transplantation From an HIV-Positive Donor to an HIV-Positive Recipient.加拿大首例关于从一名HIV阳性供体向一名HIV阳性受体进行肾脏移植的病例报告。
Can J Kidney Health Dis. 2017 Mar 2;4:2054358117695792. doi: 10.1177/2054358117695792. eCollection 2017.
2
Superior outcomes in HIV-positive kidney transplant patients compared with HCV-infected or HIV/HCV-coinfected recipients.与丙型肝炎病毒（HCV）感染或HIV/HCV合并感染的接受者相比，HIV阳性肾移植患者的预后更好。
Kidney Int. 2015 Aug;88(2):341-9. doi: 10.1038/ki.2015.74. Epub 2015 Mar 25.
3
Outcomes of kidney transplantation in HIV-infected recipients.HIV 感染者肾移植的结果。
N Engl J Med. 2010 Nov 18;363(21):2004-14. doi: 10.1056/NEJMoa1001197.
4
Renal transplantation between HIV-positive donors and recipients.HIV阳性供体与受体之间的肾移植。
N Engl J Med. 2010 Jun 17;362(24):2336-7. doi: 10.1056/NEJMc0900837.
5
Guidelines for kidney transplantation in patients with HIV disease.HIV 疾病患者肾移植指南。
HIV Med. 2006 Apr;7(3):133-9. doi: 10.1111/j.1468-1293.2006.00367.x.

英国首例关于从一名感染艾滋病毒的已故供体向两名感染艾滋病毒的受体进行肾脏移植的病例报告。

First UK case report of kidney transplantation from an HIV-infected deceased donor to two HIV-infected recipients.

作者信息

Nolan Eileen, Karydis Nikolaos, Drage Martin, Hilton Rachel

机构信息

Directorate of Transplantation, Renal and Urology, Guy's and St Thomas' NHS Foundation Trust, Guy's Hospital, Great Maze Pond, London, UK.

出版信息

Clin Kidney J. 2018 Apr;11(2):289-291. doi: 10.1093/ckj/sfx109. Epub 2017 Sep 18.

DOI:10.1093/ckj/sfx109
PMID:29644073
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5888561/
Abstract

Kidney transplantation is now considered the treatment of choice for many human immunodeficiency virus (HIV)-infected patients with end-stage renal disease (ESRD). Graft survival rates using HIV-negative donors and carefully selected HIV-positive ESRD patients are similar to those observed in HIV-uninfected kidney transplant recipients. To address the relative shortfall in donated organs it has been proposed that organs from HIV-infected deceased donors might be allocated to HIV-infected patients on the transplant waiting list. Preliminary experience in South Africa reports promising short-term outcomes in a small number of HIV-infected recipients of kidney transplants from HIV-infected donors. We sought to replicate this experience in the UK by accepting kidney offers from HIV infected deceased donors for patients with HIV-infection on the kidney transplant waiting list. Here we report the UK's first cases of kidney transplantation between HIV-positive donors and recipients.

摘要

肾移植目前被认为是许多患有终末期肾病（ESRD）的人类免疫缺陷病毒（HIV）感染者的首选治疗方法。使用HIV阴性供体以及经过精心挑选的HIV阳性ESRD患者的肾移植存活率，与未感染HIV的肾移植受者的存活率相似。为了解决捐赠器官相对短缺的问题，有人提议将来自HIV感染已故供体的器官分配给移植等待名单上的HIV感染患者。南非的初步经验报告称，少数接受来自HIV感染供体肾移植的HIV感染受者取得了令人鼓舞的短期结果。我们试图在英国复制这一经验，接受来自HIV感染已故供体的肾脏，用于肾移植等待名单上的HIV感染患者。在此，我们报告英国首例HIV阳性供体与受者之间的肾移植病例。