Langsfeld M, Nepute J, Hershey F B, Thorpe L, Auer A I, Binnington H B, Hurley J J, Peterson G J, Schwartz R, Woods J J
Department of Surgery, St. John's Mercy Medical Center, St. Louis, MO.
J Vasc Surg. 1988 Mar;7(3):395-9. doi: 10.1067/mva.1988.avs0070395.
Hemodynamic assessment of aortoiliac occlusive disease is necessary for successful arterial reconstruction of the aorta and legs. Various methods have been proposed and "pull-through" intra-arterial pressures are the "gold standard." Deep Doppler duplex imaging was supplemented with real-time spectral analysis and velocity measurements in 29 cases. Twenty-three of these patients needed arteriography. One hundred sixty-six (166) arterial segments extending from the proximal aorta to the common femoral arteries were independently graded on duplex scans and arteriograms. For severe occlusive disease, duplex scanning is highly accurate (sensitivity 82%, specificity 93%). Velocity measurements were useful in determining the hemodynamic significance of stenoses. Peak systolic velocities in stenoses were measured with a duplex scanner. The pressure gradient calculated with the modified Bernoulli equation (delta P = 4Vmax2) correlated well with the gradients measured during arteriography (r = 0.9, n = 11). These noninvasive velocity measurements and Bernoulli calculations alert arteriographers to obtain special views of suspected areas and suggest the need for "pull-through" pressures and possible balloon angioplasty. In addition, these noninvasive measurements are useful to follow up patients who have mild to moderate aortoiliac disease and after angioplasty.
对腹主动脉-髂动脉闭塞性疾病进行血流动力学评估,对于成功实施主动脉及下肢动脉重建至关重要。人们已经提出了各种方法,而“牵拉式”动脉内压力测量是“金标准”。在29例患者中,对深部多普勒双功成像补充了实时频谱分析和流速测量。其中23例患者需要进行动脉造影。对从主动脉近端至股总动脉的166个动脉节段分别进行双功扫描和动脉造影分级。对于严重闭塞性疾病,双功扫描具有很高的准确性(敏感性82%,特异性93%)。流速测量有助于确定狭窄的血流动力学意义。用双功扫描仪测量狭窄处的收缩期峰值流速。用改良的伯努利方程(ΔP = 4Vmax²)计算的压力阶差与动脉造影期间测量的阶差相关性良好(r = 0.9,n = 11)。这些非侵入性流速测量和伯努利计算可提醒动脉造影医师获取可疑区域的特殊图像,并提示需要进行“牵拉式”压力测量以及可能需要进行球囊血管成形术。此外,这些非侵入性测量对于随访轻度至中度腹主动脉-髂动脉疾病患者以及血管成形术后的患者很有用。