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经皮动脉狭窄处压力梯度的无创评估:双功超声与导管相关性研究

Noninvasive assessment of pressure gradients across iliac artery stenoses: duplex and catheter correlative study.

作者信息

Strauss A L, Roth F J, Rieger H

机构信息

Department of Medicine, Hospital for Vascular Diseases, Engelskirchen, Germany.

出版信息

J Ultrasound Med. 1993 Jan;12(1):17-22. doi: 10.7863/jum.1993.12.1.17.

DOI:10.7863/jum.1993.12.1.17
PMID:8455216
Abstract

The present study investigates prospectively the validity and accuracy of the simplified Bernoulli equation in the duplex-derived determination of pressure gradients across iliac artery stenoses in patients with occlusive artery disease. In 28 patients (age range, 38 to 76 years; mean, 53 years) with short iliac artery stenoses, we obtained both duplex scan stenotic jet velocity and catheter pressure measurements. Mean and maximum pressure gradients were determined by both methods, as was the peak-to-peak catheter gradient. The correlation between the duplex-determined and nonsimultaneously measured catheter mean pressure gradients was r = 0.77 (standard error of the estimate [SEE] = 5 mm Hg), that between the duplex-derived and catheter-determined maximum pressure gradients was r = 0.80 (SEE = 10 mm Hg), and that between maximum duplex-determined and peak-to-peak catheter gradient was r = 0.76 (SEE = 12 mm Hg). The peak-to-peak catheter gradient was significantly lower than the maximum duplex-derived gradient (46 versus 53 mm Hg, P < 0.05). Duplex-determined mean pressure gradient decreased from 15 +/- 6 to 3 +/- 1 mm Hg after balloon angioplasty of the iliac stenoses. Duplex scan can be used to predict pressure gradients across short iliac artery stenoses, provided that errors caused by angle malcompensation are prevented.

摘要

本研究前瞻性地调查了简化伯努利方程在双功超声测定闭塞性动脉疾病患者髂动脉狭窄两端压力梯度中的有效性和准确性。在28例(年龄范围38至76岁,平均53岁)患有短段髂动脉狭窄的患者中,我们同时获得了双功超声扫描的狭窄处射流速度和导管压力测量值。通过两种方法确定平均和最大压力梯度,以及导管峰 - 峰梯度。双功超声测定的与非同步测量的导管平均压力梯度之间的相关性为r = 0.77(估计标准误差[SEE]=5mmHg),双功超声得出的与导管测定的最大压力梯度之间的相关性为r = 0.80(SEE = 10mmHg),双功超声测定的最大值与导管峰 - 峰梯度之间的相关性为r = 0.76(SEE = 12mmHg)。导管峰 - 峰梯度显著低于双功超声得出的最大梯度(46对53mmHg,P <0.05)。在髂动脉狭窄进行球囊血管成形术后,双功超声测定的平均压力梯度从15±6mmHg降至3±1mmHg。只要防止角度补偿不良引起的误差,双功超声扫描可用于预测短段髂动脉狭窄两端的压力梯度。

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