Section 1, Oral Medicine, Oral Pathology & Clinical Oral Physiology, Department of Odontology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Section of Oral Biochemistry, Cariology & Endodontics, Department of Odontology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Oral Dis. 2018 Nov;24(8):1399-1416. doi: 10.1111/odi.12867. Epub 2018 Jun 7.
Saliva exerts multiple functions in relation to the initial digestive processes taking place in the upper parts of the gastrointestinal tract. Ingestion of food and beverages, in turn, is a strong stimulus for secretion of saliva with a differential composition depending on the neuronal stimulation pattern. This review paper provides insight into the mechanisms by which saliva acts in relation to taste, mastication, bolus formation, enzymatic digestion and swallowing. Also, the protective functions of saliva including maintenance of dental and mucosal integrity will be discussed as they indirectly influence the digestive process. The final part of this study focuses on the implications of xerostomia and salivary gland dysfunction on gastrointestinal functions.
唾液在与上消化道中发生的初始消化过程相关的多个功能中发挥作用。反过来,食物和饮料的摄入是刺激唾液分泌的强烈刺激因素,其组成因神经元刺激模式而异。本文综述了唾液在味觉、咀嚼、食团形成、酶消化和吞咽方面的作用机制。此外,还讨论了唾液的保护功能,包括维持牙齿和黏膜的完整性,因为它们间接影响消化过程。本研究的最后一部分重点讨论了口干和唾液腺功能障碍对胃肠道功能的影响。