Rupprecht H J, Erbel R, Brennecke R, Pop T, Jung D, Kottmeyer M, Hering R, Meyer J
II. Medizinische Klinik und Poliklinik der Universität Mainz.
Dtsch Med Wochenschr. 1988 Mar 18;113(11):409-13. doi: 10.1055/s-2008-1067653.
During a four-year period (1983-1986) percutaneous transluminal coronary angioplasty (PTCA) was performed on 930 patients with stable or unstable angina with a mortality rate of 0.4%. A transmural myocardial infarct developed in 1.1% and 1.0% of patients required an urgent aorto-coronary bypass. Thus the total rate of severe cardiac complications was 2.5%. Compared with the years 1983-1985, there was in 1986 a significant fall in the number of deaths and of myocardial infarcts from 2.2% to 0.5% (P less than 0.05), while there was a nonsignificant increase in emergency coronary bypass surgery from 0.7 to 1.3%. Patients with unstable angina compared with those with stable angina had a significantly higher mortality rate (1.0% vs. 0.2%; P less than 0.05), incidence of infarction (2.0% vs. 0.6%; P less than 0.05), and emergency operations (2.0% vs. 0.5%; P less than 0.05). The total risk of a severe cardiac complication was 1.2% for stable and 5.2% for unstable angina (P less than 0.001).
在四年期间(1983 - 1986年),对930例稳定型或不稳定型心绞痛患者进行了经皮腔内冠状动脉成形术(PTCA),死亡率为0.4%。1.1%的患者发生了透壁性心肌梗死,1.0%的患者需要紧急进行主动脉冠状动脉搭桥术。因此,严重心脏并发症的总发生率为2.5%。与1983 - 1985年相比,1986年死亡和心肌梗死的数量显著下降,从2.2%降至0.5%(P < 0.05),而急诊冠状动脉搭桥手术从0.7%增加到1.3%,差异无统计学意义。与稳定型心绞痛患者相比,不稳定型心绞痛患者的死亡率(1.0%对0.2%;P < 0.05)、梗死发生率(2.0%对0.6%;P < 0.05)和急诊手术率(2.0%对0.5%;P < 0.05)显著更高。稳定型心绞痛患者发生严重心脏并发症的总风险为1.2%,不稳定型心绞痛患者为5.2%(P < 0.001)。