Shiraki S, Tsukada K, Ozeki N, Takeuchi T, Gotoh K, Noguchi Y, Okayama Y, Matsuba S, Ohhara H, Masuko K
First Department of Internal Medicine, Nagoya City University Medical School, Japan.
Gastroenterol Jpn. 1988 Feb;23(1):37-43. doi: 10.1007/BF02918854.
The portal vein hemodynamics of patients with various liver diseases were investigated by means of a duplex system consisting of a linear electroscanner and a pulsed Doppler flowmeter. In cases of chronic liver disease, the cross-sectional area of the portal vein trunk became greater as the liver injury proceeded, while the maximum velocity tended to decrease. However, blood flow volume was no different between the controls and the chronic liver disease group. On the other hand, the splenic venous flow volume tended to increase as the liver injury advanced, suggesting that the increase in splenic venous flow volume is closely related to the formation of esophageal varices. This method permits non-invasive observation of changes during the course of various types of liver disease.
采用由线性电子扫描器和脉冲多普勒流量计组成的双功系统，对各种肝脏疾病患者的门静脉血流动力学进行了研究。在慢性肝病患者中，随着肝损伤的进展，门静脉主干的横截面积增大，而最大流速则趋于降低。然而，对照组与慢性肝病组之间的血流量并无差异。另一方面，随着肝损伤的加重，脾静脉血流量趋于增加，提示脾静脉血流量的增加与食管静脉曲张的形成密切相关。该方法能够对各种类型肝病病程中的变化进行无创观察。
