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1例晚期胃癌伴多发肝转移经S-1联合顺铂治疗后行根治性转化治疗的病例

[A Case of Advanced Gastric Cancer with Multiple Liver Metastases Treated with Curative Conversion Therapy after S-1 plus CDDP].

作者信息

Shindo Yukito, Fukuda Shinichiro, Kataoka Ryoko, Kuwamoto Nobutsuna, Takaishi Hitomi, Miura Yasuaki, Hirayama Ryoichi, Otsuka Ryo, Saito Shuji, Fujita Rikiya

机构信息

Dept. of Gastroenterology, Yokohamashinmidori General Hospital.

出版信息

Gan To Kagaku Ryoho. 2018 Mar;45(3):480-482.

Abstract

A57 -year-old man was diagnosed with advanced gastric cancer(adenocarcinoma[tub2/por1])with multiple(S3, S4, S5, S6, S8)liver and para-aortic lymph node metastases. The tumor was classified as cT4a, N3, M1, HEP, cStage IV, and the patient received chemotherapy with S-1 plus CDDP(SP). After 10 courses of SP, a CT scan revealed that the primary tumor and the metastases disappeared. The patient presented with cCR and underwent distal gastrectomy, D2 lymph node dissection, partial hepatic resection, and cholecystectomy. The histological diagnosis was classified as ypT0N0M0,(ypStage 0), pCR, and pathological Grade 3.

摘要

一名57岁男性被诊断为晚期胃癌(腺癌[tub2/por1]),伴有多发(S3、S4、S5、S6、S8)肝脏及主动脉旁淋巴结转移。肿瘤分类为cT4a、N3、M1、HEP、c期IV期,患者接受了S-1联合顺铂(SP)化疗。SP方案化疗10个疗程后,CT扫描显示原发肿瘤及转移灶消失。患者达到临床完全缓解(cCR),并接受了远端胃切除术、D2淋巴结清扫术、部分肝切除术及胆囊切除术。组织学诊断为ypT0N0M0(yp分期0期)、病理完全缓解(pCR),病理分级为3级。

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