Asaumi Yoshihide, Miyanaga Tamon, Ito Homare, Sawada Koichiro, Fujita Manami, Miyazaki Manami, Yagi Daisuke, Kitamura Hirotaka, Hirano Mitsuyasu, Maeda Kazuya, Hayashida Yuichi, Ohta Koji, Hayashi Hiroyuki, Doden Kenji, Hattori Masakazu, Hashizume Yasuo, Kaizaki Yasuharu
Dept. of Surgery, Fukui Prefectural Hospital.
Gan To Kagaku Ryoho. 2011 Aug;38(8):1325-8.
A 75-year-old man with type 4 advanced gastric cancer was referred to our hospital. We diagnosed the tumor as cStage III B(cT4a, cN2, cM0)gastric cancer. We selected neoadjuvant S-1 combined with CDDP therapy for him. After 2 courses of chemotherapy, the extension of the gastric wall improved. After an additional 2 courses of chemotherapy, the primary tumor revealed a partial response(PR), judged from a barium meal study and upper GI endoscopic findings, and a total gastrectomy with lymph node dissection was performed. The pathological specimens showed no cancer cells in the gastric wall and lymph nodes, so the histological effect was judged as Grade 3.
一名75岁的4型晚期胃癌男性患者被转诊至我院。我们将该肿瘤诊断为cⅢB期（cT4a，cN2，cM0）胃癌。我们为他选择了新辅助S-1联合顺铂治疗。经过2个疗程的化疗，胃壁增厚情况有所改善。再经过2个疗程的化疗后，根据钡餐检查和上消化道内镜检查结果判断，原发肿瘤出现部分缓解（PR），随后进行了全胃切除术及淋巴结清扫术。病理标本显示胃壁和淋巴结中无癌细胞，因此组织学疗效判定为3级。
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