Tanaka Satoshi, Ando Kei, Kobayashi Kazuyoshi, Hida Tetsuro, Seki Taisuke, Suzuki Koji, Ito Kenyu, Tsushima Mikito, Morozumi Masayoshi, Machino Masaaki, Ota Kyotaro, Ishiguro Naoki, Hasegawa Yukiharu, Imagama Shiro
a Department of Orthopaedic Surgery , Nagoya University Graduate School of Medicine , Nagoya , Japan.
b Department of Endocrinology and Metabolism , Fujita Health University , Toyoake , Japan.
Mod Rheumatol. 2019 May;29(3):491-495. doi: 10.1080/14397595.2018.1465645. Epub 2018 May 3.
Locomotive syndrome (LS) is a condition requiring nursing care for musculoskeletal disorders. Our aim was to evaluate the correlation between body composition, measured by bioelectrical impedance analysis (BIA), and LS, measured using the 25-question Geriatric Locomotive Functional Scale (GLFS-25).
We enrolled 286 individuals who were undergoing regular health follow-up. All individuals completed the GLFS-25, body composition analysis by BIA, and five physical performance tests related to LS: timed up-and-go test, 10-m gait time, maximum stride length, back strength, and grip strength. Measured variables and demographic data were compared between individuals with and without LS.
The extracellular water ratio, the extracellular water/total body water (ECW/TBW) ratio differentiated the LS and non-LS groups (p=.005), with all physical function measures being lower among individuals with a high, compared to low, ECW/TBW ratio. The risk ratio for LS among individuals with a high ECW/TBW ratio was 2.31, with an odds ratio of 2.67.
The ECW/TBW ratio is predictive of LS. Based on our results, we propose that BIA should routinely be performed, with follow-up and intervention, as needed, for individuals with a high ECW/TBW ratio, as they are at risk for developing LS.
运动机能不全综合征（LS）是一种需要对肌肉骨骼疾病进行护理的病症。我们的目的是评估通过生物电阻抗分析（BIA）测量的身体成分与使用25个问题的老年运动机能功能量表（GLFS-25）测量的LS之间的相关性。
我们招募了286名正在接受定期健康随访的个体。所有个体均完成了GLFS-25、通过BIA进行的身体成分分析以及与LS相关的五项身体机能测试：计时起立行走测试、10米步态时间、最大步幅长度、背部力量和握力。比较了有LS和无LS个体之间的测量变量和人口统计学数据。
细胞外水比率，即细胞外水/总体水（ECW/TBW）比率区分了LS组和非LS组（p = 0.005），与低ECW/TBW比率的个体相比，高ECW/TBW比率个体的所有身体机能指标均较低。高ECW/TBW比率个体患LS的风险比为2.31，优势比为2.67。
ECW/TBW比率可预测LS。基于我们的结果，我们建议对于ECW/TBW比率高的个体应常规进行BIA，并根据需要进行随访和干预，因为他们有患LS的风险。
