Krasić Dragan, Trajković Miloš, Mihailović Dragan, Krasić Staša, Živković Igor, Spasić Milan, Živković Nikola
Srp Arh Celok Lek. 2016 Sep-Oct;144(9-10):531-4.
Mucoepidermoid carcinoma, compared to other tumors of salivary glands, occurs in 5–10% of cases. Histopathologically, it is divided into a well differentiated tumor that is of low-grade of malignancy, and a medium and poorly differentiated tumor of high grade of malignancy. Central mucoepidermoid carcinoma (CMEC) of the mandible was firstly described by Lepp in 1936, on a 66-year-old female patient. CMEC is characterized by atypical clinical image and radiological manifestation.
A 55-year-old female patient was examined at the Clinic of Dentistry in Niš, Serbia, with anamnestic data regarding the presence of painless swelling in the right side of the mandible. Considering the histopathological results and presence of enlarged lymph nodes, right hemimandibulectomy and tumour excision from pterygomandibular space followed by supraomohyoid neck dissection was done. In due course, postoperative radiotherapy was applied (60 Gy)
CMEC represents a rare tumor, characterized by local tissue destruction and ability to metastasize. Initial biopsy represented the key in preoperative planing. Radical excision with neck lymph node dissection followed by postoperative radiotherapy in our case represent a successful method of treating CMEC of the mandible.
与其他唾液腺肿瘤相比，黏液表皮样癌的发病率为5%-10%。在组织病理学上，它分为恶性程度低的高分化肿瘤和恶性程度高的中分化及低分化肿瘤。下颌骨中央黏液表皮样癌（CMEC）最早由莱普于1936年在一名66岁女性患者身上描述。CMEC具有非典型的临床影像和放射学表现。
一名55岁女性患者在塞尔维亚尼什牙科诊所接受检查，有下颌骨右侧无痛性肿胀的既往史。考虑到组织病理学结果及肿大淋巴结的存在，实施了右半侧下颌骨切除术及翼下颌间隙肿瘤切除术，随后进行了肩胛舌骨肌上颈清扫术。在适当的时候，进行了术后放疗（60 Gy）。
CMEC是一种罕见肿瘤，其特征为局部组织破坏和转移能力。初次活检是术前规划的关键。在我们的病例中，根治性切除加颈部淋巴结清扫术，随后进行术后放疗，是治疗下颌骨CMEC的一种成功方法。
