父亲的疾病活动与炎症性肠病男性受孕困难有关。
Paternal Disease Activity Is Associated With Difficulty in Conception Among Men With Inflammatory Bowel Diseases.
机构信息
Division of Gastroenterology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.
Division of Gastroenterology and Hepatology, Department of Medicine, University of North Carolina, Chapel Hill, North Carolina.
出版信息
Clin Gastroenterol Hepatol. 2019 Jan;17(1):203-204. doi: 10.1016/j.cgh.2018.04.001. Epub 2018 Apr 11.
Abstract
The impact of inflammatory bowel disease (IBD) activity and treatment on fertility and pregnancy outcomes is important for men and women. In women, remission at conception determines better pregnancy outcomes, and most maternal IBD medication exposures are safe. In contrast, less is known about the impact of paternal disease activity and medication use on fertility and pregnancy outcomes in men with IBD..
摘要
炎症性肠病（IBD）活动和治疗对男性和女性的生育和妊娠结局有重要影响。对于女性来说，受孕时的缓解可决定更好的妊娠结局，且大多数母体 IBD 药物暴露是安全的。相比之下，对于患有 IBD 的男性，其疾病活动和药物使用对生育和妊娠结局的影响知之甚少。
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