眼肌型重症肌无力
Ocular Myasthenia.
作者信息
Al-Haidar Mohammed, Benatar Michael, Kaminski Henry J
机构信息
Department of Neurology, George Washington University, 2150 Pennsylvania Avenue, Northwest, Washington, DC 20037, USA; Department of Neurology, 1150 Northwest 14th Street #715, Miami, FL 33136, USA.
Department of Neurology, George Washington University, 2150 Pennsylvania Avenue, Northwest, Washington, DC 20037, USA; Department of Neurology, 1150 Northwest 14th Street #715, Miami, FL 33136, USA.
出版信息
Neurol Clin. 2018 May;36(2):241-251. doi: 10.1016/j.ncl.2018.01.003.
Ocular myasthenia is a form of myasthenia gravis in which weakness is restricted to the ocular muscles and may produce significant visual disability. Patients present with fluctuating ptosis, diplopia, or a combination of both. Examination may show any type of ocular motility deficit ranging from isolated muscle palsy to complete ophthalmoplegia. Cogan lid twitch, enhanced ptosis, peek sign, and saccadic fatigue are specific examination findings that support the clinical diagnosis of myasthenia gravis. Confirmation of the diagnosis is challenging with autoantibody serology, and repetitive nerve stimulation studies are often negative.
眼肌型重症肌无力是重症肌无力的一种形式，其肌无力仅限于眼肌，可导致严重的视力障碍。患者表现为上睑下垂、复视或两者兼有，且症状波动。检查可能显示任何类型的眼球运动障碍，从孤立的肌肉麻痹到完全性眼肌麻痹。科根眼睑抽搐、上睑下垂加重、窥视征和眼球扫视疲劳是支持重症肌无力临床诊断的特异性检查发现。通过自身抗体血清学确诊具有挑战性，重复神经电刺激检查结果通常为阴性。
Zotero 插件