Key Laboratory of Textile Science & Technology, Ministry of Education, College of Textiles, Donghua University, Shanghai, 201620, China.
Innovation Center for Textile Science and Technology, Donghua University, Shanghai, 200051, China.
Macromol Rapid Commun. 2018 May;39(10):e1800058. doi: 10.1002/marc.201800058. Epub 2018 Apr 14.
Nanofiber-based hydrogels (NFHGs) prepared by the combination of traditional hydrogels and novel nanofibers have demonstrated great potential in various application fields, owing to their integrated advantages of superhydrophilicity, high water-holding capacity, good biocompatibility, enhanced mechanical strength, and excellent structural tenability. In this review, a comprehensive overview of the structure design and synthetic strategy of NFHGs derived from electrospinning technique, weaving, freeze-drying, 3D printing, and molecular self-assembling method is provided. The widely researched multifunctional applications, primarily involving tissue engineering, drug delivery, sensing, intelligent actuator, and oil/water separation are also presented. Furthermore, some unsolved scientific issues and possible directions for future development of this field are also intensively discussed.
基于纳米纤维的水凝胶（NFHGs）通过传统水凝胶与新型纳米纤维相结合制备而成，由于其具有超亲水性、高持水能力、良好的生物相容性、增强的机械强度和优异的结构可调节性等综合优势，在各个应用领域都展现出了巨大的潜力。在本综述中，提供了源自静电纺丝技术、编织、冷冻干燥、3D 打印和分子自组装方法的 NFHGs 的结构设计和合成策略的全面概述。还介绍了广泛研究的多功能应用，主要涉及组织工程、药物输送、传感、智能执行器和油水分离。此外，还深入讨论了该领域一些未解决的科学问题和未来发展的可能方向。
