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[流感疫苗接种对大加那利岛初级医疗保健工作者和普通人群的影响:一项横断面研究]

[Effect of influenza vaccination in Primary Healthcare workers and the general population in Gran Canaria: A cross-sectional study].

作者信息

Martín-Rodríguez María Del Mar, Díaz-Berenguer José Antonio, Alonso-Bilbao José Luis, Cabeza-Mora Antonio, Navarro-Vázquez Francisco, Espiñeira-Francés Alberto, Nuez-Herrera Lidia

机构信息

Área Técnica, Gerencia de Atención Primaria de Gran Canaria, Las Palmas, España.

Área Técnica, Gerencia de Atención Primaria de Gran Canaria, Las Palmas, España.

出版信息

Aten Primaria. 2019 May;51(5):300-309. doi: 10.1016/j.aprim.2017.11.010. Epub 2018 Apr 12.

Abstract

OBJECTIVE

To estimate the effect of the influenza vaccination in Primary Healthcare workers and the general population vaccinated during the 2015/2016 campaign.

DESIGN

Cross-sectional study.

SETTING

All the Primary Healthcare centres within the Gran Canaria healthcare region.

PARTICIPANTS

A total of 1,868 Primary Healthcare workers (33.5% men; 66.5% women) and 795,605 individuals from the general population (49.4% men; 50.6% women).

PRINCIPAL MEASUREMENTS

The outcome variables in Primary Healthcare workers were: influenza cases reported to the Epidemiological Surveillance System, and the sick leave days due to illness. In the general population: reported flu cases and vaccination coverage in connection with the vaccination status of the healthcare professional. The magnitude of association between vaccination and morbidity was estimated applying logistic regression models.

RESULTS

Although not statistically significant, healthcare professionals that were not vaccinated had 1.7-fold increase in the risk of having influenza than those vaccinated. In the general population the association was significant in the female population (OR: 1.3; 95%CI: 1.1-1.5). Population coverage was significantly higher when both the doctor and nurse were vaccinated (OR: 1.3; 95%CI: 1.3-1.3), and reported flu cases decreased when the nurse was vaccinated (OR: 0.9; 95%CI: 0.9-0.9).

CONCLUSION

A possible protective effect of influenza vaccination was observed in the general population, as well as an influence of Primary Healthcare workers on the patients regarding this. Even so, the low coverages registered point to a need to implement measures that may lead to a more favourable attitude towards influenza vaccination.

摘要

目的

评估2015/2016年度流感疫苗接种运动期间,初级医疗保健工作者及普通人群接种流感疫苗的效果。

设计

横断面研究。

地点

大加那利岛医疗保健区域内的所有初级医疗保健中心。

参与者

共有1868名初级医疗保健工作者(男性占33.5%;女性占66.5%)以及795605名普通人群(男性占49.4%;女性占50.6%)。

主要测量指标

初级医疗保健工作者的结果变量为:向流行病学监测系统报告的流感病例数,以及因病请假天数。普通人群的结果变量为:报告的流感病例数以及与医疗保健专业人员接种状况相关的疫苗接种覆盖率。应用逻辑回归模型估计疫苗接种与发病率之间的关联程度。

结果

尽管无统计学意义,但未接种疫苗的医疗保健专业人员患流感的风险比接种疫苗者高1.7倍。在普通人群中,这种关联在女性人群中具有统计学意义(比值比:1.3;95%置信区间:1.1 - 1.5)。当医生和护士都接种疫苗时,人群疫苗接种覆盖率显著更高(比值比:1.3;95%置信区间:1.3 - 1.3),且当护士接种疫苗时,报告的流感病例数减少(比值比:0.9;95%置信区间:0.9 - 0.9)。

结论

在普通人群中观察到流感疫苗接种可能具有保护作用,并且初级医疗保健工作者在此方面对患者有影响。即便如此,所记录的低接种覆盖率表明需要采取措施,以促使人们对流感疫苗接种形成更积极的态度。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac7b/6837105/5f677687c87e/gr1.jpg

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