防治蜱虫及其传播疾病……展望未来。
Controlling ticks and tick-borne diseases…looking forward.
机构信息
SaBio, Instituto de Investigación en Recursos Cinegéticos IREC (CSIC-UCLM-JCCM), Ronda de Toledo s/n, 13005 Ciudad Real, Spain; Department of Veterinary Pathobiology, Center for Veterinary Health Sciences, Oklahoma State University, Stillwater, OK 74078, USA, USA.
出版信息
Ticks Tick Borne Dis. 2018 Jul;9(5):1354-1357. doi: 10.1016/j.ttbdis.2018.04.001. Epub 2018 Apr 10.
Tick-borne diseases (TBDs) represent a growing burden for human and animal health worldwide. Several approaches including the use of chemicals with repellency and parasiticidal activity, habitat management, genetic selection of hosts with higher resistance to ticks, and vaccines have been implemented for reducing the risk of TBDs. However, the application of latest gene editing technologies in combination with vaccines likely combining tick and pathogen derived antigens and other control measures should result in the development of effective, safe, and environmentally sound integrated control programs for the prevention and control of TBDs. This paper is not a review of current approaches for the control of ticks and TBDs, but an opinion about future directions in this area.
蜱传疾病（TBDs）在全球范围内对人类和动物的健康构成了越来越大的负担。为了降低 TBDs 的风险，已经采取了几种方法，包括使用具有驱避和杀虫活性的化学物质、栖息地管理、对具有更高抗蜱能力的宿主进行基因选择，以及疫苗接种。然而，将最新的基因编辑技术与疫苗结合应用，可能结合蜱和病原体衍生的抗原以及其他控制措施，有望为 TBDs 的预防和控制制定出有效、安全和对环境无害的综合控制计划。本文不是对控制蜱和 TBDs 的当前方法的综述，而是对该领域未来方向的看法。
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