Kessler J, Markowitsch H J, Denzler P, Klonner-Klopp M
Department of Psychology, University of Konstanz, Federal Republic of Germany.
Int J Neurosci. 1988 Jan;38(1-2):1-9. doi: 10.3109/00207458809000476.
The performance of juvenile Down syndrome individuals and two groups of oligophrenes was compared in several cognitive tests. All three groups of subjects were of the same CA, the Down's and one group of mentally retarded non-Down's had an average MA of 62, the other group an MA of 86 months. Though the group with the highest mental age usually outperformed the other two, significant differences were rare. It is concluded that at this age Down's and mentally retarded with different etiologies generally have rather similar cognitive abilities and that the intellectual deterioration of Down's, which at a later age inevitably leads to Alzheimer's disease, indeed starts only at a later CA.
在多项认知测试中，对患有唐氏综合征的青少年个体与两组智力缺陷者进行了比较。所有三组受试者的实际年龄相同，唐氏综合征组和一组非唐氏综合征的智力迟钝者平均心理年龄为62个月，另一组心理年龄为86个月。尽管心理年龄最高的组通常表现优于其他两组，但显著差异很少见。研究得出结论，在这个年龄段，唐氏综合征患者和病因不同的智力迟钝者通常具有相当相似的认知能力，而唐氏综合征患者的智力衰退，在晚年不可避免地会导致阿尔茨海默病，实际上是在更高的实际年龄才开始的。
