Cooper S A, Prasher V P
Rockingham Forest NHS Trust, Kettering, England.
J Intellect Disabil Res. 1998 Aug;42 ( Pt 4):293-300. doi: 10.1046/j.1365-2788.1998.00135.x.
Dementia commonly occurs in elderly people with intellectual disability, especially those with Down's syndrome. The non-cognitive symptoms of dementia can be of greater significance to individuals and carers than the cognitive changes caused by this condition. It is not known whether there are differences between people with Down's syndrome and those with intellectual disability of other causes with regard to the prevalence of such symptoms. The present study was undertaken to draw a comparison between a group with Down's syndrome and dementia (n = 19), and a group with intellectual disability of other causes and dementia (n = 26). Maladaptive behaviours and psychiatric symptomatology were assessed in both groups. The group with Down's syndrome had a higher prevalence of low mood, restlessness/excessive overactivity, disturbed sleep, being excessively uncooperative and auditory hallucinations. Aggression occurred with greater frequency in those subjects with intellectual disability of other causes. These findings are of epidemiological importance in terms of service planning and understanding psychiatric presentation.
痴呆症常见于患有智力障碍的老年人,尤其是唐氏综合征患者。痴呆症的非认知症状对患者本人及其照料者而言,可能比该病症所导致的认知变化更为重要。目前尚不清楚唐氏综合征患者与其他病因导致智力障碍的患者在这些症状的患病率方面是否存在差异。本研究旨在比较一组患有唐氏综合征和痴呆症的患者(n = 19)与另一组由其他病因导致智力障碍并患有痴呆症的患者(n = 26)。对两组患者的适应不良行为和精神症状进行了评估。患有唐氏综合征的患者组中,情绪低落、坐立不安/活动过度、睡眠障碍、极度不合作和幻听的患病率较高。攻击行为在其他病因导致智力障碍的患者中出现的频率更高。就服务规划和理解精神症状表现而言,这些发现具有流行病学意义。