• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

双侧纯原发性非妊娠性卵巢绒毛膜癌极为罕见病例。

Extremely Rare Case of Bilateral Pure Primary Non-Gestational Ovarian Choriocarcinoma.

作者信息

Syed Moinullah, Meshram Shefali, Deshpande Pooja, Parida Bikash

机构信息

Department of Radiodiagnosis, Byramjee Jeejeebhoy Government Medical College and Sassoon General Hospitals, Poona, Maharashtra, India.

出版信息

Pol J Radiol. 2017 Sep 15;82:547-550. doi: 10.12659/PJR.902578. eCollection 2017.

DOI:10.12659/PJR.902578
PMID:29657619
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5894037/
Abstract

BACKGROUND

Germ cell tumors of the ovary constitute less than one percent of ovarian tumors worldwide. Choriocarcinoma arising from the ovary is very rare and only occasionally reported in the literature. Herein, we report a case of bilateral non-gestational pure primary ovarian choriocarcinoma that was confirmed by beta human chorionic gonadotropin (β-HCG) levels and histopathology.

CASE REPORT

Our case is of a middle-aged multiparous female who presented with amenorrhea for three months. She underwent an evaluation with ultrasound (US), computed tomography (CT), and magnetic resonance imaging (MRI), which revealed bilateral bulky solid adnexal masses. Based on an increased blood level of the beta human chorionic gonadotropin and a histopathological examination, the diagnosis of bilateral non-gestational pure primary ovarian choriocarcinoma was made.

CONCLUSIONS

The imaging findings were found to be specific for bilateral non-gestational pure primary ovarian choriocarcinoma.

摘要

背景

在全球范围内，卵巢生殖细胞肿瘤占卵巢肿瘤的比例不到1%。卵巢原发性绒毛膜癌非常罕见，文献中仅有偶尔报道。在此，我们报告一例经β-人绒毛膜促性腺激素（β-HCG）水平及组织病理学确诊的双侧非妊娠性纯原发性卵巢绒毛膜癌病例。

病例报告

我们的病例是一位经产妇中年女性，出现闭经3个月。她接受了超声（US）、计算机断层扫描（CT）和磁共振成像（MRI）检查，结果显示双侧附件区有巨大实性肿块。基于β-人绒毛膜促性腺激素水平升高及组织病理学检查，诊断为双侧非妊娠性纯原发性卵巢绒毛膜癌。

结论

影像学表现被发现对双侧非妊娠性纯原发性卵巢绒毛膜癌具有特异性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/65da/5894037/3041078f9d52/PJR-82-902578-g012.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/65da/5894037/ab1544bfd0af/PJR-82-902578-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/65da/5894037/d3c6814fcd43/PJR-82-902578-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/65da/5894037/574dc2ae1ef5/PJR-82-902578-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/65da/5894037/a520d555d7e6/PJR-82-902578-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/65da/5894037/5cb35355f0a0/PJR-82-902578-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/65da/5894037/fe399ea7628f/PJR-82-902578-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/65da/5894037/175e6fcd9cdd/PJR-82-902578-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/65da/5894037/90f4d1ecbf5c/PJR-82-902578-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/65da/5894037/89aedb0f613f/PJR-82-902578-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/65da/5894037/6d265f1319a8/PJR-82-902578-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/65da/5894037/053b7e2676a1/PJR-82-902578-g011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/65da/5894037/3041078f9d52/PJR-82-902578-g012.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/65da/5894037/ab1544bfd0af/PJR-82-902578-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/65da/5894037/d3c6814fcd43/PJR-82-902578-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/65da/5894037/574dc2ae1ef5/PJR-82-902578-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/65da/5894037/a520d555d7e6/PJR-82-902578-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/65da/5894037/5cb35355f0a0/PJR-82-902578-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/65da/5894037/fe399ea7628f/PJR-82-902578-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/65da/5894037/175e6fcd9cdd/PJR-82-902578-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/65da/5894037/90f4d1ecbf5c/PJR-82-902578-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/65da/5894037/89aedb0f613f/PJR-82-902578-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/65da/5894037/6d265f1319a8/PJR-82-902578-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/65da/5894037/053b7e2676a1/PJR-82-902578-g011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/65da/5894037/3041078f9d52/PJR-82-902578-g012.jpg

相似文献

1
Extremely Rare Case of Bilateral Pure Primary Non-Gestational Ovarian Choriocarcinoma.双侧纯原发性非妊娠性卵巢绒毛膜癌极为罕见病例。
Pol J Radiol. 2017 Sep 15;82:547-550. doi: 10.12659/PJR.902578. eCollection 2017.
2
Rare occurrence of ovarian choriocarcinoma: ultrasound evaluation.卵巢绒毛膜癌的罕见病例：超声评估
J Ultrasound. 2025 Mar;28(1):213-216. doi: 10.1007/s40477-023-00868-3. Epub 2024 Feb 26.
3
A poor prognostic metastatic nongestational choriocarcinoma of the ovary: a case report and the literature review.卵巢转移性非妊娠绒毛膜癌预后不良 1 例报告并文献复习
J Ovarian Res. 2021 Apr 22;14(1):56. doi: 10.1186/s13048-021-00810-3.
4
Pure primary non-gestational choriocarcinoma originating in the ovary: A case report and literature review.起源于卵巢的纯原发性非妊娠性绒毛膜癌：一例报告及文献复习
Rare Tumors. 2021 Oct 8;13:20363613211052506. doi: 10.1177/20363613211052506. eCollection 2021.
5
Imaging in gynecological disease (22): clinical and ultrasound characteristics of ovarian embryonal carcinomas, non-gestational choriocarcinomas and malignant mixed germ cell tumors.妇科疾病影像学（二十二）：卵巢胚胎性癌、非妊娠绒毛膜癌和恶性混合生殖细胞肿瘤的临床和超声特征。
Ultrasound Obstet Gynecol. 2021 Jun;57(6):987-994. doi: 10.1002/uog.23529.
6
A pure non-gestational ovarian choriocarcinoma with delayed solitary brain metastases: Case report and review of the literature.一例伴有延迟性孤立性脑转移的纯非妊娠性卵巢绒毛膜癌：病例报告及文献复习
J Neurosci Rural Pract. 2015 Oct-Dec;6(4):578-81. doi: 10.4103/0976-3147.169869.
7
Primary Ovarian Choriocarcinoma: Rare Entity.原发性卵巢绒毛膜癌：罕见实体。
Case Rep Obstet Gynecol. 2021 Sep 24;2021:4545375. doi: 10.1155/2021/4545375. eCollection 2021.
8
Pure choriocarcinoma of ovary diagnosed by fine needle aspiration cytology.经细针穿刺细胞学检查诊断的卵巢纯绒毛膜癌
Indian J Pathol Microbiol. 2009 Jul-Sep;52(3):417-20. doi: 10.4103/0377-4929.55013.
9
A rare case of gestational ovarian choriocarcinoma coexistent with intrauterine pregnancy.罕见病例：妊娠合并宫内妊娠性绒癌。
Taiwan J Obstet Gynecol. 2022 Jul;61(4):708-712. doi: 10.1016/j.tjog.2021.09.036.
10
Primary non-gestational pure choriocarcinoma arising in the ovary: A case report and literature review.原发性卵巢非妊娠性纯绒毛膜癌：一例报告及文献复习
Oncol Lett. 2015 May;9(5):2109-2111. doi: 10.3892/ol.2015.2985. Epub 2015 Feb 26.

引用本文的文献

1
A rare case of pure non-gestational ovarian choriocarcinoma: Diagnostic mimicry and management strategies.纯非妊娠性卵巢绒毛膜癌1例罕见病例：诊断上的相似情况及处理策略
Oncoscience. 2025 Jul 28;12:70-78. doi: 10.18632/oncoscience.622. eCollection 2025.
2
Non-gestational Choriocarcinoma of the Ovary: A Report of a Rare Case From Saudi Arabia.卵巢非妊娠性绒毛膜癌：沙特阿拉伯1例罕见病例报告
Cureus. 2024 Aug 9;16(8):e66487. doi: 10.7759/cureus.66487. eCollection 2024 Aug.
3
Nongestational ovarian choriocarcinoma with bilateral teratoma: A rare case report and literature review.

本文引用的文献

1
Double Pathology: Malignant Epithelial Ovarian Tumor and Germ Cell Tumor (Choriocarcinoma), a Rare Coexistence.双重病理：恶性上皮性卵巢肿瘤与生殖细胞肿瘤（绒毛膜癌）罕见并存
World J Oncol. 2015 Aug;6(4):421-425. doi: 10.14740/wjon848w. Epub 2015 Aug 27.
2
Primary non-gestational pure choriocarcinoma arising in the ovary: A case report and literature review.原发性卵巢非妊娠性纯绒毛膜癌：一例报告及文献复习
Oncol Lett. 2015 May;9(5):2109-2111. doi: 10.3892/ol.2015.2985. Epub 2015 Feb 26.
3
Pure choriocarcinoma of the ovary: a case report.
非妊娠性卵巢绒毛膜癌合并双侧畸胎瘤：一例罕见病例报告及文献复习
Medicine (Baltimore). 2024 May 3;103(18):e36996. doi: 10.1097/MD.0000000000036996.
4
Non-Gestational Ovarian Choriocarcinoma: A Rare Ovarian Cancer Subtype.非妊娠性卵巢绒毛膜癌：一种罕见的卵巢癌亚型。
Diagnostics (Basel). 2022 Feb 22;12(3):560. doi: 10.3390/diagnostics12030560.
5
Non-gestational uterine choriocarcinoma inside a leiomyoma: importance of early suspicion in prognosis.子宫肌瘤内非妊娠性子宫绒毛膜癌：早期怀疑对预后的重要性。
BMJ Case Rep. 2022 Feb 28;15(2):e246731. doi: 10.1136/bcr-2021-246731.
6
Clinicopathological factors and prognosis analysis of 39 cases of non-gestational ovarian choriocarcinoma.39 例非妊娠性卵巢绒毛膜癌的临床病理因素与预后分析。
Arch Gynecol Obstet. 2020 Apr;301(4):901-912. doi: 10.1007/s00404-020-05502-9. Epub 2020 Mar 17.
单纯卵巢绒癌：一例报告。
J Gynecol Oncol. 2011 Jun 30;22(2):135-9. doi: 10.3802/jgo.2011.22.2.135.
4
Pure ovarian choriocarcinoma: report of two cases.纯卵巢绒毛膜癌：两例报告。
J Res Med Sci. 2009 Sep;14(5):327-30.
5
Pure non-gestational choriocarcinoma of the ovary diagnosed by DNA polymorphism analysis.通过DNA多态性分析诊断的卵巢纯非妊娠性绒毛膜癌。
Pathol Int. 2006 Oct;56(10):613-6. doi: 10.1111/j.1440-1827.2006.02016.x.
6
Imaging of pure primary ovarian choriocarcinoma.纯原发性卵巢绒毛膜癌的影像学表现
AJR Am J Roentgenol. 2004 Jun;182(6):1603-4. doi: 10.2214/ajr.182.6.1821603.
7
Primary pure ovarian choriocarcinoma mimicking ectopic pregnancy: a report of fulminant progression.酷似异位妊娠的原发性纯卵巢绒毛膜癌：暴发性进展病例报告
Tumori. 2004 Jan-Feb;90(1):136-8. doi: 10.1177/030089160409000127.
8
Management of early ovarian cancer: germ cell and sex cord-stromal tumors.早期卵巢癌的管理：生殖细胞肿瘤和性索间质肿瘤
Gynecol Oncol. 1994 Dec;55(3 Pt 2):S62-72.
9
Germ cell tumors.生殖细胞肿瘤
Curr Top Pathol. 1992;85:165-202. doi: 10.1007/978-3-642-75941-3_6.