Efficacy and Safety Evaluation of High-density Intense Pulsed Light in the Treatment of Grades II and IV Acne Vulgaris as Monotherapy in Dark-skinned Women of Child Bearing Age.

Acne vulgaris is a self-limiting, chronic inflammatory disorder of the pilosebaceous unit characterized by exacerbations and remissions. It is often the early manifestation of puberty, and in girls it appears relatively early. In women, acne tends to become aggravated during the menstrual period, pregnancy, and in those who are on progesterone. Acne treatment is divided into two parts: topical and systemic. For Grades 1 and 2 acne, topical treatment is sufficient, while for Grades 3 and 4 acne, systemic drugs such as tetracyclines and retinoids are required to control the symptoms. Chemical peeling with glycolic and salicylic acids, cryosurgery with liquid nitrogen or carbon dioxide, and narrowband ultraviolet light are a few of the supportive procedural treatments available for Grades 3 and 4 acne. The author sought to determine the efficacy and safety of intense pulsed light (IPL) therapy (Magma-F-SR; FormaTK Systems, Tirat Carmel, Israel) in the treatment of Grades 3 and 4 acne as monotherapy in women of child-bearing age. One-hundred female patients with Grades 3 and 4 acne were enrolled in this study. All patients were treated with IPL using a 530nm to 1,200nm filter once a week for a total duration of six weeks. Patient and physician scores were assessed at Weeks 1 and 6 after the last treatment. Clinical photographs were also reviewed to determine the degree of efficacy. Adverse effects were noted. Eighty percent of the patients involved in this study reported a significant reduction in lesion count compared to baseline. The adverse events were minimal-to-mild erythema. IPL therapy with 530nm to 1,200nm filter is an effective and safe modality of treatment as monotherapy in managing inflammatory Grades 3 and 4 of acne vulgaris in women of child-bearing age.