Şeyhoğlu Emrah, Erden Abdülsamet, Kılıç Levent, Karadağ Ömer, Akdağlı Sevtap Arıkan, Akdoğan Ali, Kalyoncu Umut
Department of Internal Medicine, Hacettepe University School of Medicine, Ankara, Turkey.
Division of Rheumatology, Department of Internal Medicine, Hacettepe University School of Medicine, Ankara, Turkey.
Eur J Rheumatol. 2018 Mar;5(1):75-78. doi: 10.5152/eurjrheum.2016.15081.
The use of anti-tumor necrosis factor alpha (anti-TNF-α) agents has increased during the past decade in rheumatology practice. Opportunistic infections have been reported with anti-TNF-α agents in clinical trials and post-marketing usage. Aspergillus infection is a rare opportunistic infection that is associated with immunosuppression, and there are reported cases of pulmonary aspergillosis in various rheumatic diseases treated with anti-TNF-α agents. Here, we present the first case of pulmonary aspergillosis associated with infliximab treatment in a patient with Still's disease.
在过去十年中，抗肿瘤坏死因子α（抗TNF-α）药物在风湿病治疗中的使用有所增加。在临床试验和上市后使用中，已有抗TNF-α药物导致机会性感染的报道。曲霉感染是一种与免疫抑制相关的罕见机会性感染，在用抗TNF-α药物治疗的各种风湿性疾病中，有肺部曲霉病的病例报道。在此，我们报告了第一例与英夫利昔单抗治疗相关的斯蒂尔病患者肺部曲霉病病例。
