中性理论与表型进化。
Neutral Theory and Phenotypic Evolution.
机构信息
Department of Ecology and Evolutionary Biology, University of Michigan, Ann Arbor, MI.
出版信息
Mol Biol Evol. 2018 Jun 1;35(6):1327-1331. doi: 10.1093/molbev/msy065.
Abstract
Although the neutral theory of molecular evolution was proposed to explain DNA and protein sequence evolution, in principle it could also explain phenotypic evolution. Nevertheless, overall, phenotypes should be less likely than genotypes to evolve neutrally. I propose that, when phenotypic traits are stratified according to a hierarchy of biological organization, the fraction of evolutionary changes in phenotype that are adaptive rises with the phenotypic level considered. Consistently, molecular traits are frequently found to evolve neutrally whereas a large, random set of organismal traits were recently reported to vary largely adaptively. Many more studies of unbiased samples of phenotypic traits are needed to test the general validity of this hypothesis.
摘要
尽管分子进化的中性理论被提出是为了解释 DNA 和蛋白质序列的进化，但从理论上讲，它也可以解释表型进化。然而，总体而言，表型应该比基因型更不可能以中性方式进化。我提出，当根据生物组织层次结构对表型特征进行分层时，考虑到的表型水平越高，表型进化的适应性变化比例就越高。一致地，分子特征经常被发现以中性方式进化，而最近报道的大量随机生物体特征也有很大的适应性变化。需要更多的、无偏的表型特征样本研究来检验这一假说的普遍有效性。
相似文献
1
Neutral Theory and Phenotypic Evolution.中性理论与表型进化。
Mol Biol Evol. 2018 Jun 1;35(6):1327-1331. doi: 10.1093/molbev/msy065.
2
Testing the neutral hypothesis of phenotypic evolution.检验表型进化的中性假说。
Proc Natl Acad Sci U S A. 2017 Nov 14;114(46):12219-12224. doi: 10.1073/pnas.1710351114. Epub 2017 Oct 31.
3
Rates of phenotypic evolution of ecological characters and sexual traits during the Tanganyikan cichlid adaptive radiation.坦干伊喀慈鲷辐射适应过程中生态特征和性特征表型进化率。
J Evol Biol. 2011 Nov;24(11):2378-88. doi: 10.1111/j.1420-9101.2011.02365.x. Epub 2011 Aug 16.
4
The molecular origins of evolutionary innovations.进化创新的分子起源。
Trends Genet. 2011 Oct;27(10):397-410. doi: 10.1016/j.tig.2011.06.002. Epub 2011 Aug 27.
5
Phenotype adjustment promotes adaptive evolution in a game without conflict.表型调整在无冲突博弈中促进适应性进化。
Theor Popul Biol. 2015 Jun;102:16-25. doi: 10.1016/j.tpb.2015.03.004. Epub 2015 Mar 20.
6
Divergent evolution during an experimental adaptive radiation.实验性适应性辐射过程中的趋异进化。
Proc Biol Sci. 2003 Aug 7;270(1524):1645-50. doi: 10.1098/rspb.2003.2408.
7
The evolutionary consequences of epigenesis and neutral change: A conceptual approach at the organismal level.表型发生与中性变化的进化后果：机体水平的概念方法。
J Exp Zool B Mol Dev Evol. 2023 Dec;340(8):531-540. doi: 10.1002/jez.b.23023. Epub 2020 Dec 31.
8
Evolution of adaptive phenotypic traits without positive Darwinian selection.没有正向达尔文选择的适应性表型性状的进化。
Heredity (Edinb). 2012 Apr;108(4):347-53. doi: 10.1038/hdy.2011.97. Epub 2011 Nov 2.
9
Evolution in the light of fitness landscape theory.适应度景观理论视角下的进化。
Trends Ecol Evol. 2019 Jan;34(1):69-82. doi: 10.1016/j.tree.2018.10.009. Epub 2018 Dec 21.
10
Contemporary evolution during invasion: evidence for differentiation, natural selection, and local adaptation.入侵过程中的当代进化：分化、自然选择和局部适应的证据
Mol Ecol. 2015 May;24(9):1999-2017. doi: 10.1111/mec.13162. Epub 2015 Apr 20.
引用本文的文献
1
Transcriptomic and proteomic effects of gene deletion are not evolutionarily conserved.基因缺失的转录组学和蛋白质组学效应在进化上并不保守。
Genome Res. 2025 Mar 18;35(3):512-521. doi: 10.1101/gr.280008.124.
2
Neutral drift upon threshold-like selection promotes variation in antibiotic resistance phenotype.类阈值选择下的中性漂变促进抗生素耐药表型的变异。
Nat Commun. 2024 Dec 30;15(1):10813. doi: 10.1038/s41467-024-55012-4.
3
Aridification and major geotectonic landscape change shaped an extraordinary species radiation across a world's extreme elevational gradient.干旱化和主要大地构造景观变化塑造了一个非凡的物种辐射，跨越了世界极端海拔梯度。
Commun Biol. 2024 Nov 13;7(1):1500. doi: 10.1038/s42003-024-07181-7.
4
Where the "ruber" Meets the Road: Using the Genome of the Red Diamond Rattlesnake to Unravel the Evolutionary Processes Driving Venom Evolution.橡胶之路：利用红钻响尾蛇基因组揭示驱动毒液进化的演化过程。
Genome Biol Evol. 2024 Sep 3;16(9). doi: 10.1093/gbe/evae198.
5
A new perspective on microRNA-guided gene regulation specificity, and its potential generalization to transcription factors and RNA-binding proteins.一种新的 miRNA 指导基因调控特异性的观点，及其对转录因子和 RNA 结合蛋白的潜在普适性。
Nucleic Acids Res. 2024 Sep 9;52(16):9360-9368. doi: 10.1093/nar/gkae694.
6
The role of neutral and adaptive evolutionary processes on patterns of genetic diversity across small cave-dwelling populations of Icelandic Arctic charr ().中性和适应性进化过程对冰岛北极红点鲑小型洞穴栖息种群遗传多样性模式的作用。
Ecol Evol. 2024 May 20;14(5):e11363. doi: 10.1002/ece3.11363. eCollection 2024 May.
7
The metabolic domestication syndrome of budding yeast.出芽酵母的代谢驯化综合征。
Proc Natl Acad Sci U S A. 2024 Mar 12;121(11):e2313354121. doi: 10.1073/pnas.2313354121. Epub 2024 Mar 8.
8
Principles of metabolome conservation in animals.动物代谢组保守性原则。
Proc Natl Acad Sci U S A. 2023 Aug 29;120(35):e2302147120. doi: 10.1073/pnas.2302147120. Epub 2023 Aug 21.
9
Environmental selection, rather than neutral processes, best explain regional patterns of diversity in a tropical rainforest fish.环境选择而非中性过程最能解释热带雨林鱼类的区域性多样性模式。
Heredity (Edinb). 2023 Jun;130(6):368-380. doi: 10.1038/s41437-023-00612-x. Epub 2023 Mar 30.
10
Evolution of central neural circuits: state of the art and perspectives.中枢神经回路的演化：最新进展与展望。
Nat Rev Neurosci. 2022 Dec;23(12):725-743. doi: 10.1038/s41583-022-00644-y. Epub 2022 Oct 26.
本文引用的文献
1
Human C-to-U Coding RNA Editing Is Largely Nonadaptive.人类 C 到 U 的编码 RNA 编辑在很大程度上是非适应性的。
Mol Biol Evol. 2018 Apr 1;35(4):963-969. doi: 10.1093/molbev/msy011.
2
Evolutionary adaptations to new environments generally reverse plastic phenotypic changes.对新环境的进化适应通常会逆转可塑性表型变化。
Nat Commun. 2018 Jan 24;9(1):350. doi: 10.1038/s41467-017-02724-5.
3
Most m6A RNA Modifications in Protein-Coding Regions Are Evolutionarily Unconserved and Likely Nonfunctional.蛋白质编码区域中的大多数m6A RNA修饰在进化上不保守，可能无功能。
Mol Biol Evol. 2018 Mar 1;35(3):666-675. doi: 10.1093/molbev/msx320.
4
Testing the neutral hypothesis of phenotypic evolution.检验表型进化的中性假说。
Proc Natl Acad Sci U S A. 2017 Nov 14;114(46):12219-12224. doi: 10.1073/pnas.1710351114. Epub 2017 Oct 31.
5
The fitness cost of mis-splicing is the main determinant of alternative splicing patterns.错配拼接的代价是决定可变拼接模式的主要因素。
Genome Biol. 2017 Oct 30;18(1):208. doi: 10.1186/s13059-017-1344-6.
6
A-to-I RNA editing is developmentally regulated and generally adaptive for sexual reproduction in .A-to-I RNA 编辑受发育调控，通常有利于 的有性生殖。
Proc Natl Acad Sci U S A. 2017 Sep 12;114(37):E7756-E7765. doi: 10.1073/pnas.1702591114. Epub 2017 Aug 28.
7
RATE TESTS FOR SELECTION ON QUANTITATIVE CHARACTERS DURING MACROEVOLUTION AND MICROEVOLUTION.宏观进化和微观进化过程中定量性状选择的速率测试
Evolution. 1988 Sep;42(5):1085-1089. doi: 10.1111/j.1558-5646.1988.tb02526.x.
8
Intra and Interspecific Variations of Gene Expression Levels in Yeast Are Largely Neutral: (Nei Lecture, SMBE 2016, Gold Coast).酵母中基因表达水平的种内和种间变异大多是中性的：（内讲座，2016年SMBE，黄金海岸）
Mol Biol Evol. 2017 Sep 1;34(9):2125-2139. doi: 10.1093/molbev/msx171.
9
STATISTICAL TESTS FOR NATURAL SELECTION ON QUANTITATIVE CHARACTERS.对数量性状自然选择的统计检验
Evolution. 1977 Jun;31(2):442-444. doi: 10.1111/j.1558-5646.1977.tb01025.x.
10
NATURAL SELECTION AND RANDOM GENETIC DRIFT IN PHENOTYPIC EVOLUTION.表型进化中的自然选择与随机遗传漂变
Evolution. 1976 Jun;30(2):314-334. doi: 10.1111/j.1558-5646.1976.tb00911.x.
Zotero 插件