J Trop Pediatr. 2019 Feb 1;65(1):55-62. doi: 10.1093/tropej/fmy011.
To evaluate the state of iodine nutrition in post-iodation scenario, 3500 children were examined clinically for endemic goitre. Iodine and thiocyanate were measured in 240 urine samples; iodine content in 210 salt samples was measured. Total goitre prevalence was 6.1%. Median urinary iodine level was 21.80 µg/dl, and mean (±SD) urinary thiocyanate was 0.89 ± 0.49 mg/dl. Iodine content of only 11.9% salt samples was below recommended level of 15 ppm, 25.2% was between 15 and 30 ppm and 62.9% was >30 ppm. Iodine deficiency disorders are thus clinically mild public health problem of the studied population; however, they have no biochemical iodine deficiency. Studied population found exposed to thiocyanate load that might be the possible cause for persistence of endemic goitre. People of Kolkata should be advised to eat commonly consumed goitrogenic foods after boiling and decanting the water. Periodical monitoring and evaluation of iodine status should be mandatory.
为了评估碘后环境下碘营养状况，对 3500 名儿童进行了地方性甲状腺肿临床检查。检测了 240 份尿样中的碘和硫氰酸盐，测量了 210 份盐样中的碘含量。总甲状腺肿患病率为 6.1%。尿碘中位数为 21.80µg/dl，尿硫氰酸盐平均值（±SD）为 0.89±0.49mg/dl。只有 11.9%的盐样中的碘含量低于 15ppm 的推荐水平，25.2%在 15-30ppm 之间，62.9%大于 30ppm。因此，碘缺乏症在临床上是该人群轻度的公共卫生问题，但没有生化碘缺乏。研究人群发现接触了硫氰酸盐负荷，这可能是地方性甲状腺肿持续存在的原因。应建议加尔各答的人们在煮沸和倒出饮用水后食用常见的致甲状腺肿食物。必须定期监测和评估碘状况。
