Lanska D J, Lavine L, Lanska M J, Schoenberg B S
Department of Neurology, University Hospitals of Cleveland, OH 44106.
Neurology. 1988 May;38(5):769-72. doi: 10.1212/wnl.38.5.769.
The first analysis of multiple cause-of-death data for Huntington's disease in the United States was performed, using data from the National Center for Health Statistics for the period 1971 and 1973 through 1978. The overall mortality rate was 2.27 per million population per year, approximately 80% higher than the corresponding rate for deaths in which Huntington's disease was listed as the underlying cause of death. Age-specific mortality rates peaked around age 60. Rates were similar for both sexes, and higher in whites than nonwhites. Age-adjusted rates were similar for United States whites and reported values from the Scandinavian countries. The leading causes of death were pneumonia and heart disease. Other common causes of death were nutritional deficiencies; mental disorders; cerebrovascular disorders; and accidents, poisonings, and violence. Suicide was rarely reported.
利用美国国家卫生统计中心1971年、1973年至1978年期间的数据，首次对美国亨廷顿舞蹈症的多种死因数据进行了分析。总体死亡率为每年每百万人口2.27人，比将亨廷顿舞蹈症列为根本死因的相应死亡率高出约80%。特定年龄死亡率在60岁左右达到峰值。男女死亡率相似，白人高于非白人。美国白人和斯堪的纳维亚国家报告的年龄调整率相似。主要死因是肺炎和心脏病。其他常见死因包括营养缺乏；精神障碍；脑血管疾病；以及事故、中毒和暴力。自杀报告很少。
