Department of Ophthalmology, Kindai University Faculty of Medicine, Osaka, Japan.
Asia Pac J Ophthalmol (Phila). 2018 May-Jun;7(3):156-159. doi: 10.22608/APO.201867. Epub 2018 Mar 27.
Coats disease is a sporadic, chronic retinal vascular disorder with telangiectatic and aneurysmal retinal vessels, with retinal exudation and retinal detachment in severe cases. Various treatment modalities have been used, including laser therapy, cryotherapy, anti‒vascular endothelial growth factor (VEGF) therapy, and surgery. Anti-VEGF therapy seems to be effective in reducing exudative changes and is often combined with other treatment modalities. For severe cases with exudative retinal detachment, external drainage of subretinal fluid with or without vitrectomy is commonly performed, combined with laser therapy and/or cryotherapy. Relatively good anatomical outcomes have been reported; however, postoperative functional results, particularly in young patients and/or severe cases, seem to be limited.
coats 病是一种散发性、慢性视网膜血管疾病,伴有毛细血管扩张和动脉瘤性视网膜血管,严重者可出现视网膜渗出和视网膜脱离。已采用多种治疗方法,包括激光治疗、冷冻治疗、抗血管内皮生长因子(VEGF)治疗和手术。抗 VEGF 治疗似乎可有效减少渗出性改变,且常与其他治疗方法联合应用。对于渗出性视网膜脱离严重的病例,通常采用伴有或不伴有玻璃体切除术的视网膜下液外引流,联合激光治疗和/或冷冻治疗。已报道有较好的解剖学结果;但术后功能结果,特别是在年轻患者和/或严重病例中,似乎受到限制。