Lipovetskiĭ B M, Konstantinov V O, Il'ina G N
Ter Arkh. 1988;60(1):14-8.
A total of 2096 males born in 1916-1935, residing by 1976 in the Petrogradsky District of Leningrad, were twice examined (with an interval of 7.6 yrs) using epidemiological methods. This group was equal to 53.6% of the persons subjected to the first screening. Data on the dead and those who had not come to the second screening, were not analyzed. The total frequency of nonfatal CHD from 1976 up to 1984 raised from 12.6 to 19.2%. As was shown by the assessment of a WHO questionnaire with relation to angina of effort and an analysis of ECG at rest, CHD was undetectable during the second screening in some of the examinees with CHD detected during the first screening. Further on the angina syndrome was not reaffirmed in 52.3% of the patients with previously diagnosed angina, "ischemic" ECG changes were not recorded in 37.1% of the persons with previously detected ischemic codes. Positive ECG time course was noted in 52.1% of the persons with ECG changes typical of CHD detected during the first screening. In spite of a marked tendency to an increase in the total CHD frequency a long-term observation demonstrated a possibility of a favorable time course of chronic CHD and remission in this disease.
共有2096名出生于1916年至1935年、截至1976年居住在列宁格勒彼得罗夫斯基区的男性,采用流行病学方法接受了两次检查(间隔7.6年)。该组人数占首次筛查总人数的53.6%。未对死亡者及未参加第二次筛查者的数据进行分析。1976年至1984年非致死性冠心病的总发生率从12.6%升至19.2%。根据世界卫生组织关于劳力性心绞痛问卷的评估以及静息心电图分析显示,在首次筛查中检测出患有冠心病的部分受检者在第二次筛查时未检测出冠心病。此外,在先前诊断为心绞痛的患者中,52.3%的患者未再次出现心绞痛综合征;在先前检测出有缺血性心电图改变的患者中,37.1%的患者未记录到“缺血性”心电图变化。在首次筛查中检测出具有典型冠心病心电图改变的患者中,52.1%的患者心电图呈阳性病程。尽管冠心病总发生率有明显上升趋势,但长期观察表明慢性冠心病有可能出现良好的病程及病情缓解。