Alhazzani Adel A, Alqahtani Mohammed S, Alahmari Mohammed S, Asiri Muhannad A, Alamri Noof M, Sarhan Leen A, Alkhashrami Shahad S, Asiri Abdullmgeed A
Department of Neurology, King Abdulaziz Medical City, National Guard Health Affairs, Riyadh, Kingdom of Saudi Arabia. E-mail:
Neurosciences (Riyadh). 2018 Apr;23(2):140-147. doi: 10.17712/nsj.2018.2.20170335.
To determine the quality of life (QoL) among multiple sclerosis (MS) patients in Kingdom of Saudi Arabia.
A cross-sectional study was carried out to assess the QoL of MS patients during the period from November 2016 to May 2017. Patients were recruited from tertiary hospitals in 5 regions in the kingdom. Clinical and demographic data were collected and information on patients health status using the self-report SF-36 questionnaire to assess QoL. The Patient Determined Disease Steps (PDDS) was used to measure disability. Data were analyzed using descriptive statistics, the Mann-Whitney test, the Kruskal Wallis test and Spearmans coefficient correlation.
From the 598 MS patients studied, 384 (64.2%) were female. The mean score for males was higher than females in all SF-36 QoL subscales. The mean age was 32.4 years (SD=8.4). The mean duration of illness was 6.5 years. Patients had the lowest scores in role motioning/emotional scale (mean=42.6, SD=43.3). The PDDS was negatively correlated with all SF-36 QoL subscales. Self Report-36 QoL for MS patients differed significantly through demographic characteristics at a level of significance of 0.05.
Multiple Sclerosis patients have a low QoL score and need more comprehensive management by their treating physicians. Further development of the registration will provide access to the entire population of MS patients and help comprehensively analyze the factors that affect the quality of their lives.
确定沙特阿拉伯王国多发性硬化症（MS）患者的生活质量（QoL）。
于2016年11月至2017年5月期间开展一项横断面研究，以评估MS患者的生活质量。从沙特王国5个地区的三级医院招募患者。收集临床和人口统计学数据，并使用自我报告的SF-36问卷收集患者健康状况信息，以评估生活质量。采用患者确定疾病阶段（PDDS）来衡量残疾程度。使用描述性统计、曼-惠特尼检验、克鲁斯卡尔-沃利斯检验和斯皮尔曼系数相关性分析数据。
在研究的598例MS患者中，384例（64.2%）为女性。在所有SF-36生活质量子量表中，男性的平均得分高于女性。平均年龄为32.4岁（标准差=8.4）。平均病程为6.5年。患者在角色活动/情感量表中的得分最低（平均=42.6，标准差=43.3）。PDDS与所有SF-36生活质量子量表呈负相关。MS患者的自我报告-36生活质量在人口统计学特征方面存在显著差异，显著性水平为0.05。
多发性硬化症患者的生活质量得分较低，需要其治疗医生进行更全面的管理。进一步完善登记工作将有助于了解所有MS患者的情况，并有助于全面分析影响他们生活质量的因素。
