维生素A缺乏对红细胞膜ATP酶活性及转运功能的影响

[Effect of vitamin A deficiency on ATPase activity and the transport functions of erythrocyte membranes].

作者信息

Cherviak M N

出版信息

Vopr Pitan. 1988 Jan-Feb(1):49-51.

Abstract

Influence of vitamin A deficiency on ATPase activity in erythrocytes was studied experimentally. It was shown that activity of Mg2+, Na+, K+-ATPase increased, while that of Na+, K+-ATPase decreased under such conditions. The assay of K+ and Na+ in erythrocytes and plasma revealed diminished K+ content in erythrocytes and its elevated level in plasma, Na+ concentration in erythrocytes rose. The author considers that disorders of protein biosynthesis (at the level of translation) in hypovitaminosis A are responsible for the results obtained.

摘要

通过实验研究了维生素A缺乏对红细胞中ATP酶活性的影响。结果表明，在这种情况下，Mg2+、Na+、K+-ATP酶的活性增加，而Na+、K+-ATP酶的活性降低。对红细胞和血浆中的K+和Na+进行检测发现，红细胞中的K+含量减少，血浆中的K+水平升高，红细胞中的Na+浓度升高。作者认为，维生素A缺乏症时蛋白质生物合成（在翻译水平）的紊乱是导致所得结果的原因。

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