[侵袭性B细胞淋巴瘤：德国恶性淋巴瘤能力网络参考病理学家小组关于根据2017年最新版世界卫生组织分类进行诊断程序的建议]
[Aggressive B‑cell lymphomas : Recommendations from the German Panel of Reference Pathologists in the Competence Network on Malignant Lymphomas on diagnostic procedures according to the current WHO classification, update 2017].
作者信息
Klapper W, Fend F, Feller A, Hansmann M L, Möller P, Stein H, Rosenwald A, Ott G
机构信息
Institut für Pathologie, Sektion Hämatopathologie, Universitätsklinikum Schleswig-Holstein, Campus Kiel, Arnold-Heller-Straße 3, Haus 14, 24105, Kiel, Deutschland.
Institut für Pathologie und Neuropathologie, Eberhard Karls Universität Tübingen, Tübingen, Deutschland.
出版信息
Pathologe. 2019 Mar;40(2):152-156. doi: 10.1007/s00292-018-0440-z.
The update of the 4th edition of the WHO classification for hematopoietic neoplasms introduces changes in the field of mature aggressive B‑cell lymphomas that are relevant to diagnostic pathologists. In daily practice, the question arises of which analysis should be performed when diagnosing the most common lymphoma entity, diffuse large B‑cell lymphoma. We discuss the importance of the cell of origin, the analysis of MYC translocations, and the delineation of the new WHO entities of high-grade B‑cell lymphomas.
世界卫生组织（WHO）造血系统肿瘤分类第4版的更新引入了成熟侵袭性B细胞淋巴瘤领域的一些变化，这些变化与诊断病理学家相关。在日常实践中，诊断最常见的淋巴瘤实体——弥漫性大B细胞淋巴瘤时，会出现应进行何种分析的问题。我们讨论了起源细胞的重要性、MYC易位的分析以及WHO高级别B细胞淋巴瘤新实体的界定。
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