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疫苗的不良事件及未接种疫苗的后果:一项批判性综述。

Adverse events of vaccines and the consequences of non-vaccination: a critical review.

作者信息

Aps Luana Raposo de Melo Moraes, Piantola Marco Aurélio Floriano, Pereira Sara Araujo, Castro Julia Tavares de, Santos Fernanda Ayane de Oliveira, Ferreira Luís Carlos de Souza

机构信息

Departamento de Microbiologia, Instituto de Ciências Biomédicas, Universidade de São Paulo, São Paulo, SP, Brasil.

Centro de Biotecnologia, Instituto Butantan, São Paulo, SP, Brasil.

出版信息

Rev Saude Publica. 2018;52:40. doi: 10.11606/s1518-8787.2018052000384. Epub 2018 Apr 12.

Abstract

OBJECTIVE

To analyze the risks related to vaccines and the impacts of non-vaccination on the world population.

METHODS

This is a narrative review that has considered information present in the bibliographic databases NCBI-PubMed, Medline, Lilacs, and Scientific Electronic Library Online (SciELO), between November 2015 and November 2016. For the analysis of outbreaks caused by non-vaccination, we considered the work published between 2010 and 2016.

RESULTS

We have described the main components of the vaccines offered by the Brazilian public health system and the adverse events associated with these elements. Except for local inflammatory reactions and rare events, such as exacerbation of autoimmune diseases and allergies, no causal relationship has been demonstrated between the administration of vaccines and autism, Alzheimer's disease, or narcolepsy. On the other hand, the lack of information and the dissemination of non-scientific information have contributed to the reemergence of infectious diseases in several countries in the world and they jeopardize global plans for the eradication of these diseases.

CONCLUSIONS

The population should be well informed about the benefits of vaccination and health professionals should assume the role of disseminating truthful information with scientific support on the subject, as an ethical and professional commitment to society.

摘要

目的

分析与疫苗相关的风险以及未接种疫苗对全球人口的影响。

方法

这是一篇叙述性综述,纳入了2015年11月至2016年11月期间在文献数据库NCBI - PubMed、Medline、Lilacs和科学电子图书馆在线(SciELO)中的信息。对于分析未接种疫苗引发的疫情,我们考虑了2010年至2016年期间发表的研究。

结果

我们描述了巴西公共卫生系统提供的疫苗的主要成分以及与这些成分相关的不良事件。除了局部炎症反应和罕见事件,如自身免疫性疾病和过敏症加重外,疫苗接种与自闭症、阿尔茨海默病或发作性睡病之间未显示出因果关系。另一方面,信息缺乏和非科学信息的传播导致世界上几个国家传染病再度出现,并危及全球根除这些疾病的计划。

结论

应让民众充分了解疫苗接种的益处,卫生专业人员应承担起在科学支持下传播关于该主题的真实信息的责任,这是对社会的道德和专业承诺。

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