输血传播感染：产品筛查、诊断技术及未来发展的最新进展。
Transfusion-Transmitted Infections: an Update on Product Screening, Diagnostic Techniques, and the Path Ahead.
机构信息
Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, Georgia, USA
Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, Georgia, USA.
出版信息
J Clin Microbiol. 2018 Jun 25;56(7). doi: 10.1128/JCM.00352-18. Print 2018 Jul.
Abstract
The mandated testing of blood components for infectious diseases, to prevent transfusion-transmitted infections (TTIs), began in the 1950s. Since then, changes in predonation questionnaires and advances in testing techniques have afforded more sensitive and specific tests for pathogens, in addition to allowing earlier detection. Given that these approaches have very low but detectable failure rates, the recent development and implementation of proactive pathogen reduction approaches is the new forefront of TTI prevention strategies. With globalization and the ability of pathogens to evolve rapidly, continuous redefining of testing standards and laboratory techniques is paramount for maintaining a safe blood supply.
摘要
传染病血液成分的强制性检测，以预防输血传播感染（TTIs），始于 20 世纪 50 年代。从那时起，献血前问卷的变化和检测技术的进步，除了能够更早地发现感染之外，还提供了针对病原体更敏感和更特异的检测方法。鉴于这些方法的失败率非常低但仍可检测到，因此，最近积极主动的病原体减少方法的开发和实施是 TTI 预防策略的新前沿。随着全球化和病原体快速进化的能力，不断重新定义检测标准和实验室技术对于保持安全的血液供应至关重要。
相似文献
1
Transfusion-Transmitted Infections: an Update on Product Screening, Diagnostic Techniques, and the Path Ahead.输血传播感染：产品筛查、诊断技术及未来发展的最新进展。
J Clin Microbiol. 2018 Jun 25;56(7). doi: 10.1128/JCM.00352-18. Print 2018 Jul.
2
The use of rapid diagnostic tests for transfusion infectious screening in Africa: a literature review.非洲用于输血感染筛查的快速诊断检测方法：文献综述
Transfus Med Rev. 2015 Jan;29(1):35-44. doi: 10.1016/j.tmrv.2014.09.003. Epub 2014 Sep 28.
3
Challenges for the maintaining the microbiological safety of the UK blood supply.英国血液供应微生物安全维护的挑战。
Clin Med (Lond). 2023 Mar;23(2):151-156. doi: 10.7861/clinmed.2022-0401. Epub 2023 Feb 20.
4
Efforts Toward Elimination of Infectious Agents in Blood Products.努力消除血液制品中的感染因子。
J Intensive Care Med. 2018 Oct;33(10):543-550. doi: 10.1177/0885066618756589. Epub 2018 Mar 21.
5
Pathogen reduction and blood transfusion safety in Africa: strengths, limitations and challenges of implementation in low-resource settings.非洲的病原体灭活与输血安全：资源匮乏地区实施过程中的优势、局限与挑战
Vox Sang. 2018 Jan;113(1):3-12. doi: 10.1111/vox.12620. Epub 2017 Nov 30.
6
Protecting the blood supply from emerging pathogens: the role of pathogen inactivation.保护血液供应免受新出现病原体的侵害：病原体灭活的作用。
Transfus Med Rev. 2005 Apr;19(2):110-26. doi: 10.1016/j.tmrv.2004.11.005.
7
Advances in pretransfusion infectious disease testing: ensuring the safety of transfusion therapy.输血前传染病检测的进展：确保输血治疗的安全性。
Clin Lab Med. 2002 Jun;22(2):475-90. doi: 10.1016/s0272-2712(01)00007-5.
8
The prevalence of transfusion-transmitted infections and nucleic acid testing among blood donors in Majmaah, Saudi Arabia.沙特阿拉伯麦加献血者中输血传播感染和核酸检测的流行情况。
J Infect Public Health. 2018 Sep-Oct;11(5):702-706. doi: 10.1016/j.jiph.2018.04.008. Epub 2018 Apr 24.
9
Ensuring safety of the blood supply in the United States: Donor screening, testing, emerging pathogens, and pathogen inactivation.确保美国的血液供应安全：供者筛选、检测、新出现的病原体和病原体灭活。
Semin Hematol. 2019 Oct;56(4):229-235. doi: 10.1053/j.seminhematol.2019.11.004. Epub 2019 Nov 13.
10
Pathogen reduction technology: methods, status of clinical trials, and future prospects.病原体灭活技术：方法、临床试验现状及未来前景。
Curr Hematol Rep. 2003 Nov;2(6):495-502.
引用本文的文献
1
Bridging the critical gap between infectious disease blood donation screening and connection to healthcare services: the American Chagas disease example.弥合传染病献血筛查与医疗服务联系之间的关键差距：以美国恰加斯病为例。
J Public Health Policy. 2025 Mar;46(1):168-179. doi: 10.1057/s41271-024-00539-5. Epub 2024 Dec 18.
2
Engineering Synthetic Erythrocytes as Next-Generation Blood Substitutes.工程合成红细胞作为下一代血液替代品
Adv Funct Mater. 2024 Jul 10;34(28). doi: 10.1002/adfm.202315879. Epub 2024 Feb 8.
3
Prevalence and Residual Risk of HIV in Volunteer Blood Donors of Zhejiang Province, China, from 2018 to 2022.2018年至2022年中国浙江省无偿献血者中HIV的流行率及残余风险
Can J Infect Dis Med Microbiol. 2024 May 24;2024:4749097. doi: 10.1155/2024/4749097. eCollection 2024.
4
Prevalence of hepatitis B & C infections in prospective blood donors deferred due to history of jaundice.因黄疸病史而被推迟的献血者中乙型肝炎和丙型肝炎感染的流行率。
Indian J Med Res. 2022 Jun;156(6):750-755. doi: 10.4103/ijmr.IJMR_2504_19.
5
The impact of tranexamic acid on perioperative outcomes in urological surgeries A systematic review and meta-analysis.氨甲环酸对泌尿外科手术围手术期结局的影响：一项系统评价和荟萃分析
Can Urol Assoc J. 2023 Jun;17(6):205-216. doi: 10.5489/cuaj.8254.
6
Refraining from Packed Red Blood Cells in Cardiopulmonary Bypass Priming as a Method of Neuroprotection in Pediatric Cardiac Surgery.在小儿心脏手术中，避免使用浓缩红细胞进行体外循环预充作为一种神经保护方法。
J Clin Med. 2023 Feb 12;12(4):1465. doi: 10.3390/jcm12041465.
7
Viral Metagenomics for Identification of Emerging Viruses in Transfusion Medicine.病毒宏基因组学在输血医学中新兴病毒鉴定中的应用。
Viruses. 2022 Nov 4;14(11):2448. doi: 10.3390/v14112448.
8
Anti-Viral Photodynamic Inactivation of T4-like Bacteriophage as a Mammalian Virus Model in Blood.抗病毒光动力失活 T4 样噬菌体作为血液中的哺乳动物病毒模型。
Int J Mol Sci. 2022 Sep 30;23(19):11548. doi: 10.3390/ijms231911548.
9
Assessment of dengue virus inactivation in random donor platelets using amotosalen and ultraviolet A illumination.使用补骨脂素和紫外线A照射评估随机供体血小板中登革病毒的灭活情况。
Asian J Transfus Sci. 2022 Jan-Jun;16(1):67-72. doi: 10.4103/ajts.AJTS_108_19. Epub 2022 May 26.
10
Hemoglobin Drop and the Need for Transfusion in Primary Knee Arthroplasty.初次全膝关节置换术中血红蛋白下降及输血需求
Cureus. 2022 Aug 3;14(8):e27659. doi: 10.7759/cureus.27659. eCollection 2022 Aug.
本文引用的文献
1
Inactivation of Babesia microti in red blood cells and platelet concentrates.微小巴贝斯虫在红细胞和血小板浓缩物中的灭活
Transfusion. 2017 Oct;57(10):2404-2412. doi: 10.1111/trf.14280. Epub 2017 Sep 5.
2
Creutzfeldt-Jakob disease lookback study: 21 years of surveillance for transfusion transmission risk.克雅氏病回顾性研究：21年输血传播风险监测
Transfusion. 2017 Aug;57(8):1875-1878. doi: 10.1111/trf.14145. Epub 2017 Apr 25.
3
First Zika-positive donations in the continental United States.美国本土首次出现寨卡病毒检测呈阳性的献血样本。
Transfusion. 2017 Mar;57(3pt2):762-769. doi: 10.1111/trf.14029. Epub 2017 Feb 5.
4
Screening for Babesia microti in the U.S. Blood Supply.美国血源中巴贝虫属微孢子虫的筛查。
N Engl J Med. 2016 Dec 8;375(23):2236-2245. doi: 10.1056/NEJMoa1600897.
5
Estimating the Burden of Chagas Disease in the United States.美国恰加斯病负担的估算
PLoS Negl Trop Dis. 2016 Nov 7;10(11):e0005033. doi: 10.1371/journal.pntd.0005033. eCollection 2016 Nov.
6
Prolonged Detection of Zika Virus RNA in Pregnant Women.孕妇中寨卡病毒RNA的长期检测
Obstet Gynecol. 2016 Oct;128(4):724-730. doi: 10.1097/AOG.0000000000001625.
7
Pathology of congenital Zika syndrome in Brazil: a case series.巴西先天性寨卡综合征的病理学：病例系列研究。
Lancet. 2016 Aug 27;388(10047):898-904. doi: 10.1016/S0140-6736(16)30883-2. Epub 2016 Jun 29.
8
Screening of Blood Donations for Zika Virus Infection - Puerto Rico, April 3-June 11, 2016.筛查献血者的 Zika 病毒感染情况 - 波多黎各，2016 年 4 月 3 日至 6 月 11 日。
MMWR Morb Mortal Wkly Rep. 2016 Jun 24;65(24):627-8. doi: 10.15585/mmwr.mm6524e2.
9
Zika virus: a new threat to the safety of the blood supply with worldwide impact and implications.寨卡病毒：对全球血液供应安全构成新威胁及其影响
Transfusion. 2016 Jul;56(7):1907-14. doi: 10.1111/trf.13677. Epub 2016 Jun 9.
10
AABB Committee Report: reducing transfusion-transmitted cytomegalovirus infections.AABB委员会报告：减少输血传播的巨细胞病毒感染
Transfusion. 2016 Jun;56(6 Pt 2):1581-7. doi: 10.1111/trf.13503. Epub 2016 Mar 10.
Zotero 插件