Górska I, Durko A, Kozubski W, Sokołowski P, Prusiński A
Kliniki Neurologii Akademii Medycznej w Lodzi.
Neurol Neurochir Pol. 1995 Nov-Dec;29(6):909-19.
The published results of transcranial Doppler (TCD) studies of main cerebral arteries, performed in the patients with idiopathic headaches, especially with migraine, are controversial. Some authors could not find any changes, others observed increased blood flow. These results were, however, based on single examination, and the comparison on mean velocities calculated for the whole groups. In the present study the authors decided to perform a series of TCD studies in each patient and to analyse the individual cases. It was found that blood flow velocity in the main cerebral arteries in chronic tension-type headache (8 cases) and cluster headache (7 cases) showed normal values, established for 35 healthy subjects. In migraine without aura (20 cases) and with aura (11 cases) a considerable increase (above 30%) in cerebral blood flow was found in some studies. In around 50% of the cases increased blood flow in anterior and middle cerebral arteries was found unilaterally. The authors believe that the above findings might be specific for migraine and reflect transient vasoconstriction of the vessels that, on the other head, may be the premonitory laboratory sign of the attack.
对特发性头痛尤其是偏头痛患者进行的大脑主要动脉经颅多普勒（TCD）研究的已发表结果存在争议。一些作者未发现任何变化，另一些作者则观察到血流增加。然而，这些结果基于单次检查以及对整个组计算的平均速度进行比较。在本研究中，作者决定对每位患者进行一系列TCD研究并分析个体病例。结果发现，慢性紧张型头痛（8例）和丛集性头痛（7例）患者大脑主要动脉的血流速度显示为35名健康受试者所确立的正常值。在无先兆偏头痛（20例）和有先兆偏头痛（11例）中，一些研究发现脑血流量有相当大的增加（超过30%）。在约50%的病例中，发现大脑前动脉和中动脉血流单侧增加。作者认为上述发现可能是偏头痛所特有的，反映了血管的短暂收缩，而这另一方面可能是发作的先兆实验室征象。
