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扁桃体切除术对阻塞性睡眠呼吸暂停的影响:系统评价概述

The effect of tonsillectomy on obstructive sleep apnea: an overview of systematic reviews.

作者信息

Reckley Lauren K, Fernandez-Salvador Camilo, Camacho Macario

机构信息

Otolaryngology - Head and Neck Surgery, Tripler Army Medical Center, Honolulu, HI, USA.

出版信息

Nat Sci Sleep. 2018 Apr 4;10:105-110. doi: 10.2147/NSS.S127816. eCollection 2018.

Abstract

OBJECTIVE

Tonsillectomy with adenoidectomy is a combination surgery that has been used to treat pediatric obstructive sleep apnea (OSA). For adults, tonsillectomy has also been reported as a primary treatment modality when the tissue is hypertrophied. The objective of this study is to provide an overview of published systematic reviews and meta-analyses of tonsillectomy with or without adenoidectomy as used in the treatment of OSA in children and adults.

DATA SOURCES

Nine databases, including PubMed/MEDLINE.

REVIEW METHODS

Databases were searched from their inception through July 9, 2017. The PRISMA statement was followed.

RESULTS

More than 20 recent systematic reviews and meta-analyses were identified regarding tonsillectomy as a treatment modality for OSA. There were four articles that addressed tonsillectomy's overall success, efficacy, and complications in otherwise healthy pediatric patients. Three studies evaluated tonsillectomy in obese children, and two specifically examined children with Down syndrome. Only one systematic review and meta-analysis discussed tonsillectomy as a treatment for OSA in the adult population.

CONCLUSION

Tonsillectomy as an isolated treatment modality is rarely performed in pediatric patients with OSA; however, tonsillectomy is commonly performed in combination with adenoidectomy and the combination has demonstrated efficacy as the primary treatment option for most children. In the limited adult data, tonsillectomy alone for OSA has a surprising success rate; yet, more research is required to determine long-term improvement and need for further treatment.

摘要

目的

扁桃体切除术联合腺样体切除术是一种用于治疗小儿阻塞性睡眠呼吸暂停(OSA)的联合手术。对于成人,当组织肥大时,扁桃体切除术也被报道为一种主要的治疗方式。本研究的目的是概述已发表的关于扁桃体切除术(伴或不伴腺样体切除术)用于治疗儿童和成人OSA的系统评价和荟萃分析。

数据来源

九个数据库,包括PubMed/MEDLINE。

综述方法

从数据库建立至2017年7月9日进行检索。遵循PRISMA声明。

结果

关于扁桃体切除术作为OSA治疗方式的近期系统评价和荟萃分析有20多项。有四篇文章探讨了扁桃体切除术在其他方面健康的小儿患者中的总体成功率、疗效和并发症。三项研究评估了肥胖儿童的扁桃体切除术,两项专门研究了唐氏综合征患儿。只有一项系统评价和荟萃分析讨论了扁桃体切除术作为成人OSA的治疗方法。

结论

扁桃体切除术作为一种单独的治疗方式在小儿OSA患者中很少进行;然而,扁桃体切除术通常与腺样体切除术联合进行,并且这种联合已证明是大多数儿童的主要治疗选择。在有限的成人数据中,单独进行扁桃体切除术治疗OSA的成功率惊人;然而,需要更多的研究来确定长期改善情况以及进一步治疗的必要性。

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